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| 人体椎间盘自然退变的形态学变化 | |
| 引用本文： | 王连荣,宋红星,王菊光,吴伟康.人体椎间盘自然退变的形态学变化[J].中国矫形外科杂志,2002,9(5):488-490. |
| 作者姓名： | 王连荣 宋红星 王菊光 吴伟康 |
| 作者单位： | 1. 中山大学中西医结合研究所,广州,510089 2. 中山大学附属第一医院,骨科,广州,510080 3. 日本名古屋大学医学部,生理学教研室,日本,466-8550 |
| 摘 要： | 目的：研究人体椎间盘随着年龄增长而产生显微、超微结构的增龄变化。方法：光电镜观察22例年龄27周－92岁人胸、腰椎椎间盘结构变化。结果：成人、老年人脊索细胞、软骨细胞变性坏死、胶原纤维增生、排列紊乱、断裂。年龄越大、此退变越显著。腰椎间盘软骨细胞变性坏死，胶原纤维排列紊乱、断裂比胸椎间盘更显著。结论：随着年龄增长椎间盘出现退变，腰椎间盘比胸椎间盘退变更明显。 |
| 关 键 词： | 形态学变化 椎间盘 超微结构 增龄变化 |
| 文章编号： | 1005-8478(2002)05-0488-03 |
| 修稿时间： | 2002年1月13日 |
The Morphologic Changes of Aging in Human Intervertebral Disc |
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| WANG Lian rong,SONG Hong xing,WANG Ju Guang,et al..The Morphologic Changes of Aging in Human Intervertebral Disc[J].The Orthopedic Journal of China,2002,9(5):488-490. | |
| Authors: | WANG Lian rong SONG Hong xing WANG Ju Guang |
| Institution: | WANG Lian rong,SONG Hong xing,WANG Ju Guang,et al.Institute of Integrated Traditional Chinese and Western Medicine,Sun Yat sen University,Guangzhou 510089 |
| Abstract: | Objective: To study the age related changes of ultrastructure in human intervertebral disc.Methods:The thoracic and lumbar intervertebral discs from 22 fresh cadavers between 27 weeks and 92 years old were examined with light and electron microscope.Results:In adults and old men,notochordal cell and cartilage cell appeared degeneration and necrosis,collagen appeared proliferation?irregular and gaps.The elder age and the more degeneration.The degeneration of cartilage cell and collagen fiber in lumbar disc was more serious than that in thoricic.Conclusion:The degeneration of intervertebral disc was related to aging.The degeneration of lumber disc was more serious than that of thoracic. |
| Keywords: | Intervertebral disc Morphology Microscope |
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