泮托拉唑在治疗非静脉曲张性上消化道出血中的疗效观察

目的观察泮托拉唑对非静脉曲张性上消化道出血的临床疗效。方法选择非静脉曲张性上消化道出血患者69例,随机分为两组,其中治疗组35例,对照组34例,治疗组使用泮托拉唑（泮立苏）80mg,对照组使用奥美拉唑（洛赛克）40mg,分别加入生理盐水100ml中静脉注射,每12 h 1次,观察止血效果。结果泮托拉唑治疗组显效28例,有效6例,无效1例,总有效率为97.14%,平均住院费用为（10943±2197）元。奥美拉唑对照组显效29例,有效4例,无效1例,总有效率为97.06%,平均住院费用为（12072±3083）元。两组疗效及平均住院费用比较均无显著性差异（P均〉0.05）。结论泮托拉唑能够有效治疗非静脉曲张性上消化道出血。

Clinical Observation on Therapeutic Effect of Pantoprazole on Nonvariceal Upper Gastrointestinal Bleeding

Objective To observe the therapeutic effect of pantoprazole in treating nonvariceal upper gastrointestinal bleeding.Methods A total of 69 cases patients with upper gastrointestinal bleeding were at randomly divided into observation group of 35 cases and control group of 34 cases.The intravenous drip of pantoprazol of 80mg in the observation group or omeprazole of 40 mg in the control group,twice a day for a course of treatment.The therapeutic effects were observed.Results There were 28 cases of marked effection,6 effection and 1 invalidity in the observation group.The total effective rate was 97.14%,and hospitalization expense was（10943±2197）,in the observation group.There were 29 cases of marked effection,4 effection and 1 invalidity in the control group.The total effective rate was 97.06%,and hospitalization expense was（12072±3083）,in the control group,and there was no significant difference between the effective rates and hospitalization expenses of the two groups（P〉0.05）.Conclusion It is effective with slight harmful reaction that the nonvariceal upper gastrointestinal bleeding is treated by the Pantoprazol.