Solid-phase radioimmunoassay for the detection of antibodies to collagen. |
| |
| Authors: | R B Clague R A Brown J B Weiss P J Holt |
| |
| Affiliation: | Department of Rheumatology, Stopford Building, University of Manchester, Manchester, U.K. |
| |
| Abstract: | ![]()
A solid-phase radioimmunoassay has been developed using polystyrene tubes for the detection of class-specific antibodies to collagen. The optimal conditions for the adsorption of collagen onto the tubes, followed by incubation with the antisera and finally the radiolabelled antibody to the class-specific antibody are described. Studies carried out on antisera raised in rats and rabbits using this assay confirm its sensitivity and applicability. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
