The Effect of Anticonvulsant Drugs on Blood Levels of Methotrexate |
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| Authors: | Riva Maurizio Landonio Giuseppe Defanti Carlo Alberto Siena Salvatore |
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| Affiliation: | (1) Department of Neurology, Niguarda Cà-Granda Hospital, Milan, Italy;(2) Department of Oncology, Niguarda Cà-Granda Hospital, Milan, Italy |
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| Abstract: | The reduced bioavailability of chemotherapeutic agents is one of the reasons that explains the limited efficacy of adjuvant chemotherapy in high grade glioma patients. We report how even the results of high dose sequential chemotherapy can be influenced by antiepileptic drugs. |
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| Keywords: | anticonvulsant drugs chemotherapy gliomas |
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