胚胎玻璃化冷冻技术的临床应用(附成功分娩1例报道)

目的 探讨胚胎玻璃化冷冻技术的临床应用效果。方法 运用玻璃化冷冻技术保存75例患者的397个胚胎，复苏13例69个胚胎，并根据患者的情况进行胚胎移植。结果 69个胚胎中，丢失3个，存活26个，存活率为39，4％。复苏后8例患者因胚胎质量差未移植，另外5例患者共移植了14个胚胎，其中1例获得单胎妊娠，分娩1名健康女要。结论 玻璃化冷冻技术简便、经济，并能够有效地冻存人类早期胚胎，可成为胚胎冷冻方法的另一个选择。

Clinical Application of Embryo Vitrification on Cleaved Human Embryos (One Case of Report)

Objective To evaluate the efficacy and efficiency of freezing cleaved human embryos through vitrification. Methods 397 surplus embryos from 75 women were vitrified. A total of 69 embryos from 13 women were subsequently thawed. Results From the 69 thawed embryos, 3 lost and 26 survived, with an overall embryo survival rate of 39. 4 %. In 8 women embryos could not be replaced because no transferable embryos were obtained after thawing. After the transfer of 14 embryos in 5 women, 1 woman became clinically pregnant. Conclusion Vitrification is efficacy and efficiency for cryopreservation of cleaved human embryos. It is hoped that vitrification will replace conventional cryopreservation in the future.