肺心病血清心肌酶学变化及临床意义

目的 探讨慢性肺源性心脏病患者急性发作期及临床缓解期血清心肌酶学的变化及临床意义。方法 检测25例正常人、50例肺心病急性发作期患者及16例肺心病临床缓解期患者心肌酶学变化及急性发作期患者治疗前后血清心肌酶学的变化。结果 肺心病患者血清心肌酶学明显高于健康人群，且急性发作期明显高于临床缓解期，急性发作期患者治疗前后心肌酶学差异显著。死亡组心肌酶学明显高于存活组。结论 血清心肌酶学变化可估计肺心病患者的预后及判断治疗效果。

Changes of sero-myocardial enzyme activity and their clinic significance of chronic pulmonary heart disease

Objective To explore the clmnges of sero-myocardial enzyme activity and their clinic significance of chronic pulmonary heart disease .Methods 72patients with chronic pulmonary heart disease and 25 healthy controls were examined for serum CPK , CK-MB, LDH and AST. Results The CPK , CK-MB, LDH and AST in chronic pulmonary heart disease group were higher than heathy control group .The CPK,CK-MB,LDH and AST in the acute outbreak period of chronic pulmonary heart disease group were higher than that of the alleviat group,there are lower levels of CPK ,CK-MB,LDH and AST after treatment .The average values of four sero-myocardial enzymes aetivety were significantly higher in death group than those in suivival group. Conclusion The activity of sero-myoeardial enzymes played an indicative role in patients with chronic pulmonary heart disease and were heltfful for evaluating the treatment effect.