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| Castleman病的临床病理诊断与治疗体会 | |
| 引用本文： | 刘虎,彭燕,王志华,徐兵. Castleman病的临床病理诊断与治疗体会[J]. 安徽医学, 2009, 30(8): 934-936. DOI: 10.3969/j.issn.1000-0399.2009.08.039 |
| 作者姓名： | 刘虎 彭燕 王志华 徐兵 |
| 作者单位： | 安徽省立医院小儿外科,合肥,230001;安徽省立医院小儿外科,合肥,230001;安徽省立医院小儿外科,合肥,230001;安徽省立医院小儿外科,合肥,230001 |
| 摘 要： | 目的探讨Castleman病的临床病理特点及治疗体会。方法通过常规组织病理和免疫组织化学等方法观察5例Castleman病并结合相关文献进行分析。结果该病女性多于男性,5例Castleman病中4例为透明血管型,表现为淋巴滤泡增生,滤泡生发中心变小,套区增生的淋巴细胞围绕滤泡生发中心呈同心圆状,形成特征性的＂洋葱＂样同心圆结构;1例浆细胞型滤泡间大量的成熟浆细胞增生伴淋巴窦消失,滤泡内的毛细血管穿入,＂洋葱＂样改变不明显及滤泡间可见无定型的嗜酸性物质沉积。结论Castleman病是一种特殊类型的淋巴结增生性疾病,可发生于任何年龄;其病因可能与人疱疹病毒8（HHV-8）有关,该病的诊断和分型主要依靠组织病理学;治疗方面：手术切除是首选,辅以化疗、放疗和生物治疗等多种方法联合应用,有助于控制本病的发展。 |
| 关 键 词： | Castleman病 病理诊断 治疗 |
Clinicopathologtcal diagnosis and treatment experience with Casfleman's disease |
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| Liu Hu,Peng Yan,Wang Zhihua,et al. Clinicopathologtcal diagnosis and treatment experience with Casfleman's disease[J]. Anhui Medical Journal, 2009, 30(8): 934-936. DOI: 10.3969/j.issn.1000-0399.2009.08.039 | |
| Authors: | Liu Hu Peng Yan Wang Zhihua et al |
| Affiliation: | Liu Hu,Peng Yan,Wang Zhihua,et al Department of Pathology,Anhui Provincial Hospital,Hefei 230001 |
| Abstract: | Objective To study the clinicopathological characteristics and treatment of Castleman disease.Methods From2000 to 2008 five cases of Castleman disease were observed and analyzed with literature review,according to histopathological characteristicsand immunohistochemical method.Results The females patient was more than males,4 cases were of hyaline-vasculartype which showed lymphoid follicular hyperplasia and small genminal center.Lymphocyte cells in mantle zone were concentric circles around genminal center... |
| Keywords: | Castleman disease Pathological diagnosis Treatment |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |