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度洛西汀治疗抑郁症对照研究的Meta分析
引用本文:凌云熹,阳中明. 度洛西汀治疗抑郁症对照研究的Meta分析[J]. 四川精神卫生, 2011, 24(1): 18-20
作者姓名:凌云熹  阳中明
作者单位:安徽省芜湖市第四人民医院,241002
摘    要:目的探讨度洛西汀治疗抑郁症的疗效和不良反应的差异。方法用Meta分析对9项度洛西汀与其他抗抑郁剂治疗抑郁症对照研究的文章进行再分析,并评价其合并效应量大小和综合显著性检验。结果度洛西汀治疗前后的自身对照,提示度洛西汀治疗抑郁症前后症状学变化有非常显著性差异,效应极强;度洛西汀与对照药在第2周末和治疗结束后的组间比较,提示前者起效快,且疗效优于对照药。结论度洛西汀与对照药的疗效相当,但起效快。

关 键 词:度洛西汀  抑郁症  Meta分析

Meta-analysis of comparative study on duloxetine in the treatment of depression
LING Yunxi,YANG Zhongming. Meta-analysis of comparative study on duloxetine in the treatment of depression[J]. Sichuan Mental Health, 2011, 24(1): 18-20
Authors:LING Yunxi  YANG Zhongming
Affiliation:LING Yunxi,YANG Zhongming.Wuhu 4th People's Hospital,Anhui 241002,China
Abstract:Objective To study the difference of efficacy and side effect of duloxetine in the treatment of depression.Method 9 comparative studies of duloxetine and other antidepressants in the treatment of depression were analyzed by Meta-analysis.Results The significant difference in change of symptom before and after treatment by duloxetine was found.Comparison between duloxetine and the controlled antidepressants at 2 weeks treatment and at the end of each trial showed that duloxetine had a rapid effect on symptom...
Keywords:Duloxetine Depression Meta-analysis  
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