创伤后应激障碍的记忆损害与脑结构MRI特点探讨

目的探讨创伤后应激障碍的记忆损害与脑结构MRI特点，为提高此类患者临床诊断与治疗效果提供可靠依据。材料与方法选取研究组（患者）和对照组（健康志愿者）各16例，进行记忆功能评估，所有受检者均行MRI检查，记录两组的记忆功能评估结果、MRI检查结果，进行统计学分析。结果研究组创伤后应激障碍患者理解记忆、延迟理解记忆、视觉再生、延迟视觉再生评分均显著低于对照组（P〈0．05），两组对比结果具有统计学意义；研究组患者经MRI检查可知，其脑部额叶与颞叶脑区灰质体积显著小于对照组。结论可根据创伤后应激障碍表现为记忆损害患者脑部额叶与颞叶脑区灰质体积显著小于健康人群这一显著特点，对发生严重创伤后应激障碍患者进行脑部MRI检查，从而准确判断其是否出现记忆障碍，并判断其临床治疗效果。

Study on memory function impairment and structural MRI in posttraumatic stress disorder

Objective： Study on memory function impairment and structural MRI in posttraumatic stress disorder. To provide a reliable basis for clinical improvement in patients with clinical diagnosis and treatment of such. Materials and Methods： Selected for the study group and the control group 16 cases each, memory function evaluation, and give the magnetic resonance imaging examination, assessment results, two groups were recorded in memory function magnetic resonance examination results, give statistical analysis, draw the conclusion. Results： The understanding of memory, understanding, memory, visual reproduction delay delay visual reproduction scores were significantly lower than that of the control group of healthy people, and P〈0.05 in patients with stress disorder after trauma research group, two groups of patients the results with statistical significance, the study group patients by MRI examination shows, the brain frontal and temporal lobe brain gray matter volume was significantly smaller than that of the control group healthy people. Conclusions： Clinicians according to post-traumatic stress disorder symptom is memory impairment in patients with frontal lobe of the brain gray matter volume and temporal lobe brain regions were significantly lower than healthy people this trait, to severe posttraumatic stress disorder in patients with brain MRI examination, to determine whether memory impairment, and judge the clinical treatment effect.