| Grave患者^131I治疗前后血清细胞间粘附分子—1水平的研究 |
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| 引用本文： | 吴永刚,刘国锋,苏见知,何建军,潘佑民. Grave患者^131I治疗前后血清细胞间粘附分子—1水平的研究[J]. 中国现代医学杂志, 2001, 11(8): 33-34 |
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| 作者姓名： | 吴永刚 刘国锋 苏见知 何建军 潘佑民 |
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| 作者单位： | 中南大学湘雅二医院核医学科 |
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| 摘 要： | 目的：探讨ICAM－1在Grave(GD)病发病中的作用。方法：应用ELISA法GD患者^131I治疗后不同时期血液ICAM的水平，并与正常对照组比较。结果：Grave病1周后，ICAM－1明显升高，并与FT3、FT4成正相关，6个月后ICAM－1显著低于治疗前组，但仍高于正常组。Grave眼病（GO）患者血清ICAM－1水平明显高于GD病人，而有甲亢患者ICAM－1明显高于无甲亢患者。结论：ICAM－1能动态反映GD的情况。在GO早期，宜采取激素补充治疗。
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| 关 键 词： | Grave病 细胞间粘附分子－1 放射性碘 治疗 |
| 修稿时间： | 2001-06-03 |
Serum Levels of ICAM-1 before and after 131I-Treatment of Grave's Diseases |
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| Wu Yonggang,Liu Guofeng,Su Jianzhi,et al.. Serum Levels of ICAM-1 before and after 131I-Treatment of Grave's Diseases[J]. China Journal of Modern Medicine, 2001, 11(8): 33-34 |
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| Authors: | Wu Yonggang Liu Guofeng Su Jianzhi et al. |
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| Affiliation: | Wu Yonggang,Liu Guofeng,Su Jianzhi,et al. The Department of Nuclear Medicine,The Second Xiangya Hosptial,Central South University,Changsha 410011 |
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| Abstract: | Objective:To assess the serum levels of ICAM-1 before and after 131 I-treatment of Grave's disease.Methods:We measured the serum levels of ICAM-1 of 0,1w,6M by ELISA method.Results:1. Significent increases were seen in free T 4 index(FT 41),free T 3 index(FT 31)within the first weeks,and TSH simultaneously decreased.2. The serum levels of ICAM is significant higher in GO than in non-GO and in hyperthrodism than in non-hyperthrodism.Conclusions:The elevated serum concentration of ICAM-1 in patient with GD probably reflects ongoing immune processes. |
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| Keywords: | ICAM-1 GD 131 I |
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