脑梗塞患者颈动脉粥样硬化的研究

目的:用彩色多普勒超声观察脑梗塞患者颈动脉内中膜厚度。探讨颈动脉粥样硬化的相关危险因素及其与脑梗塞的关系。方法:用彩色多普勒超声观察了128例脑梗塞患者的颈动脉超声表现,观察其颈动脉内中膜厚度及斑块形成情况,并与96例健康体检者做对照。结果:脑梗塞患者的颈动脉粥样硬化明显高于健康者,两者有显著性差异。分析发现随着年龄的增大,颈动脉斑块的发生率明显增加(P<0.01)。高血压、糖尿病及血纤维蛋白原水平与颈动脉斑块形成有密切联系(P<0.05)。但是血脂水平与斑块的形成无明确关系。颈动脉斑块组和非斑块组的吸烟、饮酒和性别无明显差异。脑梗死患者颈动脉斑块的发生率明显增加(P<0.01)。结论:颈动脉内中膜厚度与脑梗塞患者有明显的相关性,颈动脉IMT增厚和斑块形成是多因素相互作用的结果,它们是脑梗死的重要危险因素。

Study of Intima Media Thickness of Carotid Artery in Cerebral Infarction

Objective:To study the intima media thickness of carotid artery in cerebral infarction by color doppler ultra- sound,sad To investigate the risk factors of the carotid artery atherosclerosis and the association of carotid atherosclerosis with cerebral infarction.Methods:Using the colour Doppler ultrasonography technique,the carotid intimal medial thickness,posi- tion of plaques were measured at both the infarction and infarction-flee sides in 128 patients with cerebral stroke,and com- pared with 96 cases in the controlled group.Results:patients with cerebral infarction showed presence of carotid arteriosclero- sis,the incidence was significant higher than control group.By analysis,we found carotid plaque increased progressively with agn(P=0.01).It was correlated to high blood pressure,dia--betes and increased fibrinogen level(P<0.05).No relationship was found between plaque and and blood lipid levels.There was no significant difference betwen plaque group and no plaque group in smoking,drinking and gender,the incidence of carotid plaque in CI group was significantly higher than that in the control.Conclusion:Stroke occurence is closely corelated to the carotid arteriosclerotic,Using the colour Doppler ultrasonogra- phy technique to find carotid arteriosclerosis has important significance to avoid and predict stroke events.Increased CA IMT and plaque are important risk factors of CI and many factors are contributed to them.