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活血利水中药复方对颈动脉粥样硬化并血瘀证患者血管内皮功能的影响
引用本文:黄琛,钱海凌,李丽,莫霄云. 活血利水中药复方对颈动脉粥样硬化并血瘀证患者血管内皮功能的影响[J]. 中西医结合心脑血管病杂志, 2011, 9(7): 795-797
作者姓名:黄琛  钱海凌  李丽  莫霄云
作者单位:广西中医学院第一附属医院,530023
基金项目:为广西卫生厅医疗卫生重点基金课题
摘    要:目的观察活血利水中药复方对颈动脉粥样硬化并血瘀证患者血管内皮功能的影响。方法 56例入选患者随机分为两组,对照组予口服阿托伐他汀治疗,治疗组予活血利水中药复方加阿托伐他汀治疗,疗程90 d。观察患者治疗前后血瘀证证候评分、高敏C反应蛋白(hs-CRP)、血液流变学和肱动脉血管内皮舒张功能的变化。结果与对照组比较,治疗组治疗后血瘀证候评分明显减轻,hs-CRP和血液流变学水平明显好转(P<0.05),内皮依赖性舒张功能(FMD)和非内皮依赖性舒张功能(NMD)明显改善(P<0.05)。结论活血利水中药复方能改善颈动脉粥样硬化并血瘀证患者的临床症状,降低hs-CRP水平,改善血管内皮功能。

关 键 词:动脉粥样硬化  血瘀证  血管内皮功能  活血利水复方

Influence of Huoxue Lishui Decoction on Endothelial Function in Carotid Atherosclerosis with Blood Stasis Syndrome
Huang Chen,Qian Hailin,Li Li,et al The First Affiliated Hospital,Guangxi University of Traditional Chinese Medicine. Influence of Huoxue Lishui Decoction on Endothelial Function in Carotid Atherosclerosis with Blood Stasis Syndrome[J]. Chinese Journal of Integrative Medicine on Cardio-/Cerebrovascular Disease, 2011, 9(7): 795-797
Authors:Huang Chen  Qian Hailin  Li Li  et al The First Affiliated Hospital  Guangxi University of Traditional Chinese Medicine
Affiliation:Huang Chen,Qian Hailin,Li Li,et al The First Affiliated Hospital,Guangxi University of Traditional Chinese Medicine(Nanning 530023)
Abstract:Objective To investigate the influence of Huoxue Lishui decoction(HLD) on endothelial function in the patients(pts) with carotid atherosclerosis and blood stasis syndrome.Methods Fifty-six pts were randomly divided into two groups:Control group treated with atorvastatin,and treatment group treated with HLD and atorvastatin.The score of blood stasis syndrome,the levels of high sensitive C-reactive protein(hs-CRP),hemorrheology index,and brachial endothelial relaxing function were compared before and after tr...
Keywords:atherosclerosis  blood stasis syndrome  endothelial function  Huoxue Lishui decoction  
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