静脉丙种球蛋白治疗重症毛细支气管炎疗效分析

目的观察静脉丙种球蛋白(IVIG)治疗重症毛细支气管炎的临床疗效。方法将重症毛细支气管炎患儿65例随机分为治疗组34例和对照组31例。对照组给予常规综合治疗,治疗组在此基础上加用静脉丙种球蛋白400 mg/(kg.d),连用3 d,观察2组疗效。结果 2组在紫绀、喘憋、肺部罗音消失时间及住院时间比较,差异有统计学意义(P<0.05)。2组总有效率比较,差异有统计学意义(P<0.05)。结论 IVIG治疗婴幼儿重症毛细支气管炎可缩短病程,疗效确切,可在临床推广应用。

The clinical efficacy of intravenous immune globulin treatments for severe bronchiolitis

Objective To observe the clinical efficacy of intravenous immune globulin treatments for severe bronchiolitis.Methods Sixty-five patients with severe bronchiolitis were randomly divided into two groups.Thirty-four cases were in treatment group,and the rest 31 cases were in control group.The control group used regular treatment.The treatment group adopted IVIG(400 mg/(kg·d-1) in addition to the regular treatment,one injection a day for three consecutive days.Results Two groups were statistically different in purple gan,asthma suppress,lungs detect rales disappear time and hospitalization time comparison(P<0.05).The difference of total effectiveness of the two groups was statistically significant(P<0.05).Conclusion IVIG in treatment of infants with severe bronchiolitis can not only shorten the duration of symptoms,but also has definite effect.It can be clinically applied.