| ICP-MS测定聚丙烯输液瓶中6种金属元素的含量 |
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| 引用本文： | 郑景峰,徐燕慧,陈芳,陈燕华,盖毅. ICP-MS测定聚丙烯输液瓶中6种金属元素的含量[J]. 海峡药学, 2014, 0(11): 92-94 |
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| 作者姓名： | 郑景峰 徐燕慧 陈芳 陈燕华 盖毅 |
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| 作者单位： | 福建省药品检验所福州350001 |
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| 基金项目： | 国家药典委员会2013年度药品标准提高项目 |
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| 摘 要： | 目的建立电感耦合等离子体质谱（ICP-MS）法测定聚丙烯输液瓶中铜、镉、铬、铅、锡、钡6种元素含量的方法。方法采用ICP-MS法测定聚丙烯输液瓶中6种金属元素的含量。结果线性范围在0~0.3μg·m L^-1,r=0.9992~0.9999,方法检出限均优于0.0004μg·m L^-1,各元素回收率均在97.7%~100.8%之间,相对标准偏差（n=6）均〈2.0%。结论本方法灵敏度高,检出限低,分析速度快,分析精密度高,可用于测定聚丙烯输液瓶中6种金属元素的含量。
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| 关 键 词： | 电感耦合等离子体质谱(ICP-MS) 聚丙烯输液瓶 金属元素 |
Determination of 6 Elements in Polypropylene Infusion Bottles by ICP-MS |
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| ZHENG Jing-feng,XU Yan-hui,CHEN Fang,CHEN Yan-hua,GAI Yi. Determination of 6 Elements in Polypropylene Infusion Bottles by ICP-MS[J]. Strait Pharmaceutical Journal, 2014, 0(11): 92-94 |
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| Authors: | ZHENG Jing-feng XU Yan-hui CHEN Fang CHEN Yan-hua GAI Yi |
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| Affiliation: | ( Fujian Provincial Institute for Drug Control, Fuzhou 35000], China) |
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| Abstract: | OBJECTIVE To establish a ICP-MS method to determine 6 elements of Cu,Cd,Cr,Pb,Sn and Ba in polypropylene infusion bottles. METHODS The content of 6 metallic elements in polypropylene infusion bottles was determined by ICP-MS. RESULTS The linear range was 0 ~ 0. 3μg·m L^- 1while the correlation coefficient in0. 9992 ~ 0. 9999 and the detection limit was lower than 0. 0004μg·m L^- 1with recovery rate in 97. 7% ~ 100. 8%and relative standard deviation（n = 6） less than 2. 0%. COCLUSION The proposed method is sensitive,accurate and fast with a low detection limit,it can be used determination of 6 metallic elements in polypropylene infusion bottles. |
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| Keywords: | ICP-MS polypropylene infusion bottles metallic element |
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