| 十味疏风通窍颗粒的质量标准研究 |
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| 引用本文： | 王坤,张祖亮.十味疏风通窍颗粒的质量标准研究[J].海峡药学,2014(11):89-91. |
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| 作者姓名： | 王坤 张祖亮 |
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| 作者单位： | 1. 安徽省六安市中医院药剂科 六安 237000
2. 安徽省六安市食品药品检验所 六安237000 |
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| 摘 要： | 目的建立十味疏风通窍颗粒的质量标准。方法采用TLC法对颗粒中黄芪、甘草进行定性鉴别,并用HPLC-ELSD法测定颗粒中黄芪甲苷的含量。结果在TLC色谱中均能检测出黄芪甲苷和甘草,阴性无干扰。黄芪甲苷浓度范围在60.06μg·m L^-1~300.30μg·m L^-1之间呈良好的线性关系（R=0.9999）。平均加样回收率为99.44%,RSD为1.50%（n=6）。结论该方法专属性强,灵敏度高,重复性好,可用于十味疏风通窍颗粒的质量标准控制。
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| 关 键 词： | 十味疏风通窍颗粒 TLC 黄芪甲苷 HPLC |
Studies on the Quality Standard for Shiweishufengtongqiao Granules |
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| WANG Kun,ZHANG Zu-liang.Studies on the Quality Standard for Shiweishufengtongqiao Granules[J].Strait Pharmaceutical Journal,2014(11):89-91. |
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| Authors: | WANG Kun ZHANG Zu-liang |
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| Institution: | WANG Kun,ZHANG Zu-liang(1. Dept of Pharmacy The Traditional Hospital of Luan in Anhui Province, Luan 237000, China;2. Luan Inspection for Food and Drug Control, Luan 23？000, China) |
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| Abstract: | OBJECTIVE To establish the quality standard for Shiweishufengtongqiao Granules. METHODS Radix Astragali and Glycyrrhizae Radix Et Rhizoma were identified by TLC. The content of Astragaloside IV was determinated by HPLC. RESULTS Astragaloside IV and Glycyrrhizae Radix Et Rhizoma could be detectel in TLC without interferemce. The experiment showed good linear relationship at the ranges of 60. 06μg·m L^- 1~ 300. 30μg·m L^- 1for Astragaloside IV（R = 0. 9999）. The average recovery rare of chlorogenic acid was 99. 44%,RSD was1. 50%（n = 6）. CONCLUSION The established methods are not only practical but capable of effectively controlling the quality of Shiweishufengtongqiao Granules. |
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| Keywords: | Shiweishufengtongqiao Granules TLC Astragaloside IV HPLC |
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