| 吉非替尼治疗晚期非小细胞肺癌的临床观察 |
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| 引用本文： | 袁彬,王岗,吴敏慧,褚亮,赵征,吕云,袁媛,施常备.吉非替尼治疗晚期非小细胞肺癌的临床观察[J].陕西肿瘤医学,2010,18(4):720-722. |
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| 作者姓名： | 袁彬 王岗 吴敏慧 褚亮 赵征 吕云 袁媛 施常备 |
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| 作者单位： | 陕西省肿瘤医院,陕西西安710061 |
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| 摘 要： | 目的：研究吉非替尼对晚期非小细胞肺癌（NSCLC）的疗效。方法：收集13例晚期NSCLC患者,口服吉非替尼250mg/d,直到病情进展或因不良反应不能耐受为止,观察其疗效及不良反应。结果：21例中部分缓解（PR）10例,稳定（SD）7例,进展（PD）4例,缓解率47.6%,疾病控制率80.9%。结论：吉非替尼治疗晚期NSCLC患者有一定疗效,不良反应轻。
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| 关 键 词： | 非小细胞肺癌 吉非替尼 靶向治疗 |
The effects of gefitinib on the advanced non-small cell lung cancer patients |
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| YUAN Bin,WANG Gang,WU Min-hui,CHU Liang,ZHAO Zheng,LV Yun,YUAN Yuan,SHI Chang-bei.The effects of gefitinib on the advanced non-small cell lung cancer patients[J].Shaanxi Oncology Medicine,2010,18(4):720-722. |
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| Authors: | YUAN Bin WANG Gang WU Min-hui CHU Liang ZHAO Zheng LV Yun YUAN Yuan SHI Chang-bei |
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| Institution: | (Department of Zhongxi Medical Oncology,Shaanxi Tumor Hospital,Xi＇an 710061,China.) |
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| Abstract: | Objective：To evaluate the efficacy and safety of gefitinib on patients with advanced non-small cell lung cancer.Methods：Thirteen advanced non-small lung patients received gefitinib 250mg/d,qd,until disease progression or occurrence of intolerable toxicity.Results： Among 13 patients,no one got complete response,7 patients got partial response,4 patients were stable,and 2 patients developed.The totle reponse rate was 47.6%,disease control rate was 80.9%.Conclusion：Gefitinib is effective and safe in treatment of patients with advanced NSCLC. |
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| Keywords: | non-small cell lung cancer gefitinib target therapy |
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