儿童新型冠状病毒肺炎疑似病例分析

目的 分析儿童新型冠状病毒肺炎(简称新冠肺炎)疑似病例的流行病学及临床特点. 方法 选取2020年1月23日-2月23日湖南省儿童医院感染科隔离留观病房的46例新冠肺炎疑似病例进行回顾性分析. 结果 疑似病例流行病学史:有湖北旅居史的33例(71.8％),所在社区有确诊病例的7例(15.2％),接触高度疑似病例的2例(...

Suspected cases of COVID-19 in Children

Objective To analyze the epidemiological and clinical characteristics of suspected cases of COVID-19 in children. Methods We retrospectively analyzed 46 suspected COVID-19 cases from the isolation wards of Infection Department, Hunan Children’s Hospital from January 23 to February 23, 2020. Results The epidemiological history of the suspected cases displayed that there were 33(71.8%) cases having a history of travelling or living in Hubei Province, 7(15.2%) cases from communities with confirmed cases, 2(4%) cases contacting with highly suspected cases, 2(4%) cases with local detection results of SARS-CoV-2 nucleic acid suspected positive and 2(4%) cases with aggregated incidence, and all the cases had no history of direct contact with diagnosed patients. Clinical manifestations were fever or/and cough. Blood routine, C reactive protein, procalcitonin, and liver and renal functions were normal. The detection rates of influenza virus, respiratory syncytial virus and mycoplasma were 19.6%, 10.9% and 15.2%, respectively. Chest radiographs showed no specificity. All the results of SARS-CoV-2 nucleic acid tests of the suspected cases were negative. All the patients were recovered and discharged after treatment, and the follow-ups after two weeks showed all normal. Conclusions The epidemiological history of the suspected cases in children was mainly the history of travelling or living in Hubei Province, and fever was the main clinical manifestation. It is necessary to detect common pathogens such as influenza virus, respiratory syncytial virus and mycoplasma. The confirmed diagnosis rate of the suspected cases is low. Nucleic acid detection is still the main etiological diagnosis method.