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脊髓损伤组织血小板活化因子变化与脊髓水肿的关系
引用本文:肖建如 赵定麟. 脊髓损伤组织血小板活化因子变化与脊髓水肿的关系[J]. 中华创伤杂志, 1995, 11(6): 332-334
作者姓名:肖建如 赵定麟
作者单位:XIAO Jian ru,ZHAO Ding lin,ZENG Hua wu,et al. Department of Orthopaedics,Changzheng Hospital,The Second Military Medical University,Shanghai 200003
摘    要:
采用改良的Allen法打击猫脊髓致伤模型,测定伤后2小时-1周伤区及邻近脊髓组织血小板活化因子(PAF)含量及水含量。结果表明,伤后2-75小时伤区及邻近脊髓组织PAF含量及水含量较对照组明显增高,而伤后1周时与对照组无显著性差异。提示PAF在脊髓损伤后脊髓水肿的发生、发展过程中起重要作用。

关 键 词:脊髓损伤 脊髓水肿 血小板活化因子

The Relation between Alteration of Platelet Active Factor Levels in Spinal Cord Tissue and Spinal Cord Edema after Spinal Cord Injury
XIAO Jian ru,ZHAO Ding lin,ZENG Hua wu,et al.. The Relation between Alteration of Platelet Active Factor Levels in Spinal Cord Tissue and Spinal Cord Edema after Spinal Cord Injury[J]. Chinese Journal of Traumatology, 1995, 11(6): 332-334
Authors:XIAO Jian ru  ZHAO Ding lin  ZENG Hua wu  et al.
Affiliation:XIAO Jian ru,ZHAO Ding lin,ZENG Hua wu,et al. Department of Orthopaedics,Changzheng Hospital,The Second Military Medical University,Shanghai 200003
Abstract:
Spinal cord contussion in cats was made by Allen's improved method. Platelet active factor (PAF) levels and water content in injured spinal cord tissue and adjacent spinal cord tissue to the injured were measured from 2 hours to 1 week after spinal cord injury. The results showed that PAF levels and water content in the injured spinal cord tissue and the adjacent spinal cord tissue increased significantly in 2 to 72 hours after trauma as compared to the control group ( P <0.01). PAF levels and water content in the adjacent spinal cord tissue had no significant difference between 1 week after trauma group and the control group ( P >0.05). It is considered that PAF plays an important role in production and development of spinal cord edema after trauma. (Original article on page 332)
Keywords:Spinal cord injury Spinal cord edema Platelet active factor  
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