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| 微量清蛋白尿与2型糖尿病合并冠心病的关系 | |
| 引用本文： | 王为幸,李晓永,董艳. 微量清蛋白尿与2型糖尿病合并冠心病的关系[J]. 内科理论与实践, 2009, 4(3): 205-208. DOI: 10.16138/j.1673-6087.a1165 |
| 作者姓名： | 王为幸 李晓永 董艳 |
| 作者单位： | 上海交通大学医学院附属新华医院内分泌科; |
| 摘 要： | 目的:探讨2型糖尿病患者微量清蛋白尿(MA)与冠心病的关系。方法:342例2型糖尿病患者根据冠状动脉(冠脉)造影结果分为合并冠心病组(106例)和不合并冠心病组(236例),测定2组24h尿清蛋白、血糖、糖化血红蛋白及血脂等相关指标;比较MA阳性组(139例)和MA阴性组(203例)冠心病的发病率及冠脉造影特点。采用多元Logistic回归方法分析2型糖尿病患者冠脉病变的危险因素。结果:糖尿病合并冠心病组MA水平明显高于不合并冠心病组(P<0.01),多元逐步回归分析也表明MA与糖尿病患者冠心病的发生显著相关(P<0.05);MA阳性组冠心病发病率明显高于MA阴性组(42.5%比23.2%,P<0.01);此外,与MA阴性组比较,MA阳性组重度血管狭窄、弥漫性和闭塞性病变更多(P0.05)。结论:MA是2型糖尿病患者冠脉病变的重要危险因素,且伴MA的2型糖尿病合并冠心病患者冠脉病变更严重。 |
| 关 键 词： | 2型糖尿病 微量清蛋白尿 冠心病 |
Relation between microalbuminuria and coronary heart disease in type 2 diabetic patients |
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| WANG Wei-xing,LI Xiao-yong,DONG Yan. Relation between microalbuminuria and coronary heart disease in type 2 diabetic patients[J]. Joournal of Internal Medicine Concepts& Practice, 2009, 4(3): 205-208. DOI: 10.16138/j.1673-6087.a1165 | |
| Authors: | WANG Wei-xing LI Xiao-yong DONG Yan |
| Affiliation: | WANG Wei-xing,LI Xiao-yong,DONG Yan. Department of Endocrinology,Xinhua Hospital,Shanghai Jiaotong University School of Medicine,Shanghai 200092,China |
| Abstract: | Objective To investigate the relation between microalbuminuria (MA) and coronary heart disease in patients with type 2 diabetes mellitus. Methods Three hundred and forty two patients with type 2 diabetes were divided into 2 groups:diabetes without coronary artery disease(CAD) and diabetes with CAD according to the results of coronary angiography. Twenty-four-hour urinary albumin excretion rate (UAER),blood glucose,glycosylated hemoglobin and lipids were assessed,and incidence of CAD and coronary angiographi... |
| Keywords: | Type 2 diabetes mellitus Microalbuminuria Coronary heart disease |
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