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| 钝顶螺旋藻糖缀合物SPPA-1的糖链化学结构研究 | |
| 引用本文： | 王仲孚,彭志英,彭雪梅,黄琳娟,田庚元. 钝顶螺旋藻糖缀合物SPPA-1的糖链化学结构研究[J]. 药学学报, 2001, 36(5): 356-359 |
| 作者姓名： | 王仲孚 彭志英 彭雪梅 黄琳娟 田庚元 |
| 作者单位： | 1. 华南理工大学生物科学与工程研究中心 2. Shanghai Institute of Organic Chemistry Chinese Academy of Sciences |
| 摘 要： | 目的研究从钝顶螺旋藻中分离纯化得到的糖缀合物SPPA-1的糖链结构。方法应用了气相色谱、甲基化分析和1H，13CNMR及2DNMR技术研究糖链结构。结果SPPA-1的糖链是由单一葡萄糖组成，其重复单元是由1→4连接的葡萄糖糖残基组成的主链且具有分支。结论SPPA-1的糖链部分为一新的葡聚糖。 |
| 关 键 词： | 螺旋藻；多糖；结构 |
| 收稿时间： | 2000-08-21 |
STRUCTURE ELUCIDATION OF GLYCAN OF A GLYCOCONJUGATE SPPA-1 ISOLATED FROM SPIRULINA PLATENSIS |
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| WANG Zhong-fu,PENG Zhi-ying,PENG Xue-mei,HUANG Lin-juan,TIAN Geng-Yuan. STRUCTURE ELUCIDATION OF GLYCAN OF A GLYCOCONJUGATE SPPA-1 ISOLATED FROM SPIRULINA PLATENSIS[J]. Acta pharmaceutica Sinica, 2001, 36(5): 356-359 | |
| Authors: | WANG Zhong-fu PENG Zhi-ying PENG Xue-mei HUANG Lin-juan TIAN Geng-Yuan |
| Affiliation: | Center of Biological Science and Engineering, South China University of Technology, Guangzhou 510640, China. |
| Abstract: | AIM: To elucidate the structure of the glycan of SPPA-1, a glycoconjugate isolated from Spirulina platensis. METHODS: Methylation analysis, GC/MS, and 1D, 2DNMR techniques were used to determine the structures of the glycoconjugate (SPPA-1). RESULTS: SPPA-1 was only composed of alpha-D-glucose and shown to be a (1-->4) linked alpha-D-glucan to which a few glucosyl side chains are attached at O-6 of the glucosyl residues of the main chain. CONCLUSION: The glycan of SPPA-1 is a new glucan. |
| Keywords: | Spirulina platensis polysaccharide structure |
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