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| 糖基化终末产物与冠心病相关性的临床观察 | |
| 引用本文： | 杨胜荣,朱玉霞,李炀,张艳秋. 糖基化终末产物与冠心病相关性的临床观察[J]. 中国心血管杂志, 2006, 11(4): 255-256,265 |
| 作者姓名： | 杨胜荣 朱玉霞 李炀 张艳秋 |
| 作者单位： | 天津公安医院内三科,天津,300050 |
| 摘 要： | 目的探讨糖基化终末产物与冠心病的相关性。方法分别检测正常对照组、冠心病组、糖尿病组及冠心病合并糖尿病组的血清糖基化终末产物、糖化血红蛋白,并进行相关分析。结果各观察组血清糖基化终末产物均较正常对照组升高,且各组间的差异有显著性(P<0.05),糖基化终末产物与糖化血红蛋白呈正相关(r=0.738,P=0.000)。结论血清糖基化终末产物与冠心病具有相关性,并且是糖尿病心血管合并症的相关危险因素。 |
| 关 键 词： | 糖基化终末产物 冠心病 2型糖尿病 相关性分析 |
| 文章编号： | 1007-5410（2006）04-0255-03 |
| 收稿时间： | 2006-03-27 |
| 修稿时间： | 2006-03-272006-04-12 |
Clinical observations on correlation between advanced glycation end products and coronary heart disease |
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| YANG Sheng-rong,ZHU Yu-xia,LI Yang,ZHANG Yan-qiu. Clinical observations on correlation between advanced glycation end products and coronary heart disease[J]. Chinese Journal of Cardiovascular Medicine, 2006, 11(4): 255-256,265 | |
| Authors: | YANG Sheng-rong ZHU Yu-xia LI Yang ZHANG Yan-qiu |
| Affiliation: | Department of Cardiology, Tianjin Gongan Hospital, Tianjin 300050 China |
| Abstract: | Objective To explore the relationship between AGE and CHD.Methods AGE and HbA1c were tested in each group,including control,CHD,DM,both CHD and DM group.Correlative analysis was carried out.Results AGE were significantly higher in each observational group compared to that in control group(P<0.05).AGE was significantly positively correlated with HbA1c(r=0.738,P=0.000).Conclusions AGE was correlated with CHD,it's a risk factor related to diabetic cardiovascular disease. |
| Keywords: | Advanced glycation end products(AGE) Coronary heart disease(CHD) TypeⅡdiabetes mellitus(TⅡDM) Correlation analysis. |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |