局部动脉内溶栓治疗视网膜中央动脉阻塞26例报告

目的观察局部动脉内溶栓治疗视网膜中央动脉阻塞的疗效，探讨如何提高其治疗效果。方法将微导管插入眼动脉或置于颈动脉内行眼动脉造影，将10万～25万U尿激酶用100ml生理盐水稀释溶解，间断手控推人眼动脉或颈内动脉一眼动脉起始部，行溶栓治疗。结果本组26例患者中，8例术后视力由术前光感或眼前数指恢复至0．1以上，10例有中度增进，8例无明显好转。视力有所恢复的18例中，发病至溶栓时间均在8天以内，视力明显恢复的3例中，2例是在发病3天内溶栓。结论局部动脉内溶栓治疗视网膜中央动脉阻塞有明显疗效，溶栓效果与溶栓时间密切相关，溶栓治疗应尽早开始。

Selective intra-arterial thrombolytic therapy for central retinal artery occlusion:26 cases report

Objective To observe the effect of selective intra-arterial thrombolytic therapy for central retinal artery thrombosis. Methods 100 000-250 000U of urokinase were injected into the ophthalmic artery via a catheter in the ophthalmic artery or the internal carotid artery to carry out the thrombolytic therapy. Results The visual acuity was significantly improved from light perception or finger counting to 0.1 in 8 of a total of 26 cases, partially improved in 10 cases, and no change in vision in 8 cases. The time interval from the onset of the disease to thrombolysis was within 8 days in the 18 patients who showed improvement, 3 of them showed significant improvement, of whom 2 received the treatment within 3 days. Conclusion Selective intra-arterial thrombolytic therapy is effective for the treatment of central retinal artery thrombosis. The effect was closely related to the time interval from the onset of the disease to thrombolysis. The thrombolytic therapy should be carried out as soon as possible.