| 高龄孕妇子痫前期并发胎盘早剥妊娠结局分析 |
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| 引用本文： | 张慧丽,孙雯,朱泳锖,杜丽丽,林琳,陈娟娟,杜培丽,周燕媚,李雪媛,陈敦金. 高龄孕妇子痫前期并发胎盘早剥妊娠结局分析[J]. 中华产科急救电子杂志, 2021, 10(3): 160-164. DOI: 10.3877/cma.j.issn.2095-3259.2021.03.008 |
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| 作者姓名： | 张慧丽 孙雯 朱泳锖 杜丽丽 林琳 陈娟娟 杜培丽 周燕媚 李雪媛 陈敦金 |
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| 作者单位： | 1. 广州医科大学附属第三医院产科 广州市危重孕产妇救治中心 广东省产科重大疾病重点实验室 5101502. 广州市萝岗区红十字会医院妇产科，510555 |
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| 基金项目： | 广东省医学科学技术研究基金项目(A2020079); 广州市卫生健康科技项目(20201A011095); 广州医科大学附属第三医院博士启动科研项目(2018B03); 广州市科技计划市校（院）联合资助项目(202102010005); 广州市卫健委临床高新技术建设项目(2019GX03) |
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| 摘 要： | 目的 探讨高龄对子痫前期并发胎盘早剥母儿结局的影响.方法 回顾性分析2017年1月至2019年12月在广州医科大学附属第三医院住院分娩的子痫前期并发胎盘早剥、单胎妊娠患者40例,以年龄≥35岁者为高龄组(14例),年龄<35岁者为对照组(26例),比较两组患者的临床资料特点、生化指标及围产儿结局.结果(1)两组孕妇一般...
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| 关 键 词： | 子痫前期 胎盘早剥 母亲年龄 妊娠结局 |
| 收稿时间： | 2021-05-19 |
Advanced maternal age impacts pregnancy outcomes in placental abruption coupled with preeclampsia |
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| Huili Zhang,Wen Sun,Yongqiang Zhu,Lili Du,Lin Lin,Juanjuan Chen,Peili Du,Yanmei Zhou,Xueyuan Li,Dunjin Chen. Advanced maternal age impacts pregnancy outcomes in placental abruption coupled with preeclampsia[J]. Chinese Journal of Obstetric Emergency (Electronic Edition), 2021, 10(3): 160-164. DOI: 10.3877/cma.j.issn.2095-3259.2021.03.008 |
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| Authors: | Huili Zhang Wen Sun Yongqiang Zhu Lili Du Lin Lin Juanjuan Chen Peili Du Yanmei Zhou Xueyuan Li Dunjin Chen |
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| Affiliation: | 1. Department of Obstetrics and Gynecology, The Third Affiliated Hospital of Guangzhou Medical University, Guangzhou Medical Center for Critical Pregnant Women, Key Laboratory for Major Obstetric Diseases of Guangdong Province, Guangzhou 510150, China2. Luogang District Red Cross Hospital of Guangzhou, Guangzhou 510000, China |
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| Abstract: | ObjectiveTo explore associations between advanced maternal age and obstetrical and neonatal outcomes of placental abruption coupled with preeclampsia in singleton pregnancies. MethodsA retrospective study of 40 cases of placental abruption coupled with preeclampsia was performed and the subjects were collected from The Third Affiliated Hospital of Guangzhou Medical University between January 2017 and December 2019. Pregnant women were divided into two groups: advanced maternal age (AMA) group (≥35 years old) and control group (<35 years old). Data regarding maternal characteristics, laboratory evaluations, obstetrical and neonatal outcomes were compared between the groups. Results(1) Compared with control group, alanine transaminase (206.29±308.91) U/L, aspartate aminotransferase (279.86±449.01) U/L and serum creatinine (96.21±51.11) μmol/L and Urea (8.07±3.23) mmol/L were significantly higher. They also with higher systolic pressure and more maternal blood loss while the platelet was significantly lower in AMA group (P<0.05). The composite adverse neonatal outcomes including perinatal deaths and birth asphyxia were significantly higher in AMA group (P<0.05). ConclusionsPlacental abruption coupled with preeclampsia at AMA was associated with higher complication rates, such as maternal liver and kidney injury, as well as adverse neonatal outcomes. |
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| Keywords: | Preeclampsia Abruption placentae Maternal age Pregnancy outcomes |
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