自体动静脉内瘘与带隧道带涤纶套导管对维持性血液透析患者贫血的影响

目的 分别探讨自体动静脉内瘘与带隧道带涤纶套导管对维持性血液透析患者贫血症状的改善效果。方法 选择2016年2月—2018年1月期间在我院治疗的72例维持性血液透析患者为研究对象,随机分为2组,各36例,内瘘组采用自体动静脉内瘘治疗,导管组采用带隧道带涤纶套导管治疗,比较两组治疗前以及治疗12个月后血红蛋白(Hemoglobin,Hb)水平以及C反应蛋白(C-reactive protein,CRP)水平。结果 内瘘组治疗前与治疗12个月后Hb水平为(73.02±8.79)g/L、(107.71±16.95)g/L,导管组为(72.35±8.16)g/L、(105.83±20.16)g/L,治疗前与治疗12个月后,两组患者Hb水平对比,差异无统计学意义(P>0.05);两组患者治疗12个月后Hb水平均高于治疗前,差异有统计学意义(P<0.05);内瘘组治疗前与治疗12个月后CRP水平为(15.17±3.86)mg/L、(5.08±2.13)mg/L,导管组为(15.21±3.75)mg/L、(5.87±2.49)mg/L,治疗前与治疗12个月后,两组患者CRP水平对比,差异无统计学意义(P>0.05);两组患者治疗12个月后CRP水平均低于治疗前,差异有统计学意义(P<0.05)。结论 对维持性血液透析患者而言,不同血管通路(自体动静脉内瘘与带隧道带涤纶套导管)均可有效缓解贫血症状,减轻微炎症状态。

Effects of autologous arteriovenous fistula and polyester sleeve catheter with tunnel on anemia in patients with maintenance hemodialysis

Objective To investigate respectively the effects of autologous arteriovenous fistula and polyester sleeve catheter with tunnel on anemia in maintenance hemodialysis patients. Methods A total of 72 maintenance hemodialysis patients treated in a hospital from February 2016 to January 2018 were randomly divided into an internal fistula group treated with autologous arteriovenous fistula and a catheterization group treated with polyester catheter with tunnel, and there were 36 cases in each group. The levels of hemoglobin (Hb) and C-reactive protein (CRP) were detected and compared between the two groups before and 12 months after treatment. Results In the internal fistula group, the levels of Hb were (73.02±8.79) g/L and (107.71±16.95) g/L before and 12 months after treatment respectively, and in the catheterization group, they were (72.35±8.16) g/L and (105.83±20.16) g/L, respectively, and there were no significant differences in the levels of Hb between the two groups before and 12 months after treatment. However, the levels of Hb in the two groups 12 months after treatment were significantly higher than those before treatment (P<0.05). In the internal fistula group, the levels of CRP were (15.17±3.86) mg/L and (5.08±2.13) mg/ L before and 12 months after treatment respectively, and in the catheterization group, they were (15.21±3.75) mg/L and (5.87±2.49) mg/L respectively, and there were no significant differences between the two groups (P>0.05). Twelve months after treatment, the levels of CRP in both groups were lower than those before treatment (P<0.05). Conclusion In the maintenance hemodialysis patients, the different vascular accesses (autologous arteriovenous fistula and polyester sleeve catheter with tunnel) are both effective and the anemia can be relieved and the micro-inflammation state can be reduced.