白内障超声乳化吸除术联合人工晶体植入术治疗葡萄膜炎并发白内障的临床研究

目的 观察白内障超声乳化吸除术联合人工晶体植入术治疗葡萄膜炎并发白内障的临床效果。方法 选取2017年1月—2019年3月本院收治的92例(92只眼)葡萄膜炎并发白内障患者为研究对象,遵循随机对照原则将其分为对照(n=46)和观察组(n=46)。对照组行常规小切口白内障囊外切除术联合人工晶体植入术治疗,观察组行白内障超声乳化吸除术联合人工晶体植入术治疗。观察两组视力、炎症细胞计数及术后并发症情况。结果 对照组术后1周视力(0.59±0.08)及3个月视力(0.87±0.12)均低于观察组的(0.78±0.10)、(1.08±0.18),差异有统计学意义(P值均<0.05);对照组术后1周炎症细胞计数(20.67±8.36)个/0.5 mm3、1个月炎症细胞计数(8.68±4.36)个/0.5 mm3高于观察组的(14.65±6.54)个/0.5 mm3、(3.68±2.65)个/0.5 mm3,差异有统计学意义(P值均<0.05);较对照组相比,观察组术后并发症发生率较低(4.35% VS 21.74%),差异有统计学意义(P<0.05)。结论 白内障超声乳化吸除术联合人工晶体植入术可有效提高葡萄膜炎并发白内障患者视力,且术后并发症发生率低,安全性更高。

Clinical study of phacoemulsification and intraocular lens implantation in treatment of cataract with uveitis

Objective To explore the clinical effect of phacoemulsification and intraocular lens implantation in the treatment of uveitis complicated with cataract. Methods A total of 92 cases (92 eyes) of uveitis complicated with cataract were selected from January 2017 to March 2019 and they were divided into a control group (n=46) and a trial group (n=46) according to the randomized controlled principle. In the control group, the conventional small-incision extracapsular cataract extraction combined with intraocular lens implantation was performed and in the trial group, the phacoemulsification and intraocular lens implantation was performed. The vision, inflammatory cell counts, and post-operation complications of two groups were investigated. Results In the control group, the average visual acuity was (0.59±0.08) and the average visual acuity in 3 months was (0.87±0.12), which were lower than those in the trial group , and the difference was statistically significant (P<0.05). In the control group, the average inflammatory cell counts were (20.67±8.36)/0.5 mm3, and the average inflammatory cell counts in 1 month were (8.68±4.36)/0.5 mm3, which were higher than those in the trial group (both P<0.05). The incidence of post-operation complications in the trial group was 4.35%, which was lower than that in the control group (21.74%, P<0.05). Conclusion The phacoemulsification and intraocular lens implantation is effective and safe in the treatment of cataract with uveitis, and it can improve the visual acuity and reduce post-operation complications.