| 正交试验优选防感颗粒的提取工艺 |
| |
| 引用本文： | 王京霞,陈琳,陈芳,林燕飞,孙静芸.正交试验优选防感颗粒的提取工艺[J].中国现代应用药学,2015,32(4):428-432. |
| |
| 作者姓名： | 王京霞 陈琳 陈芳 林燕飞 孙静芸 |
| |
| 作者单位： | 浙江省中医院，杭州 310006,浙江省中医院，杭州 310006,浙江省中医院，杭州 310006,杭州创新中药标准化研究所有限公司，杭州 310053,杭州创新中药标准化研究所有限公司，杭州 310053 |
| |
| 摘 要： | 目的确立防感颗粒的最佳提取工艺。方法应用正交试验和HPLC,以防感颗粒中R,S-告依春、白花前胡甲素、苦杏仁苷及甘草苷4种活性成分含量为指标,采用多指标综合评分法,确定防感颗粒的提取工艺。结果防感颗粒最佳提取工艺为:药材加8倍量水,煎煮3次,每次1.5 h,乙醇浓度为60%。结论优选出的工艺稳定可靠,可用于防感颗粒的提取。
|
| 关 键 词： | 防感颗粒 R S-告依春 苦杏仁苷 白花前胡甲素 甘草苷 正交试验 提取工艺 |
| 收稿时间： | 2014/5/20 0:00:00 |
| 修稿时间： | 2015/3/31 0:00:00 |
Optimum Extracting Procedure of Fanggan Granules by Orthogonal Design |
| |
| WANG Jingxi,CHEN Lin,CHEN Fang,LIN Yanfei and SUN Jingyun.Optimum Extracting Procedure of Fanggan Granules by Orthogonal Design[J].The Chinese Journal of Modern Applied Pharmacy,2015,32(4):428-432. |
| |
| Authors: | WANG Jingxi CHEN Lin CHEN Fang LIN Yanfei and SUN Jingyun |
| |
| Institution: | Zhejiang Hospital of Traditional Chinese Medicine, Hangzhou 310006, China,Zhejiang Hospital of Traditional Chinese Medicine, Hangzhou 310006, China,Zhejiang Hospital of Traditional Chinese Medicine, Hangzhou 310006, China,Hangzhou Innovation TCM Standardization Research Institute Co., Ltd., Hangzhou 310053, China and Hangzhou Innovation TCM Standardization Research Institute Co., Ltd., Hangzhou 310053, China |
| |
| Abstract: | OBJECTIVE To establish the optimum extracting procedure of Fanggan granules. METHODS A multi index comprehensive evaluation method by orthogonal test and HPLC was used for the determination of the extracting procedure of Fanggan granules, with four active ingredients including (R,S)-epigoitrin, praeruptorin A, amygdalin and liquiritin as the content index. RESULTS The optimum extraction process of Fanggan granules was determined as follows: herbs were extracted 3 times with 8 times of water; 1.5 h each time; ethanol concentration was 60%. CONCLUSION The optimum procedure is stable and reliable for the extraction of Fanggan granules. |
| |
| Keywords: | Fanggan granules (R S)-epigoitrin amygdalin praeruptorin A liquiritin orthogonal design extracting procedure |
| 本文献已被 CNKI 等数据库收录！ |
| 点击此处可从《中国现代应用药学》浏览原始摘要信息 |
| 点击此处可从《中国现代应用药学》下载免费的PDF全文 |
|
