| 血压变异性与高血压靶器官损害的关系 |
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| 引用本文： | 上官新红 张维忠. 血压变异性与高血压靶器官损害的关系[J]. 高血压杂志, 1998, 6(3): 181-184 |
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| 作者姓名： | 上官新红 张维忠 |
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| 作者单位： | 上海第二医科大学附属瑞金医院(上官新红)，上海市高血压研究所(张维忠) |
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| 摘 要： | 目的探讨血压变异性与高血压靶器官损害的关系。方法选择６０例高血压病人进行２４ｈ动态血压监测和静息及应激状况下短时血压监测，以各时间段血压的标准差作为血压变异性指标，并测定左心室重量指数（ＬＶＭＩ）和２４ｈ尿微量蛋白（ＭＡＵ）。结果与正常对照组比较，高血压患者长时血压变异增大，静息及心算时的短时血压变异也增大；ＬＶＭＩ，ＭＡＵ与长时血压变异显著相关，但与各状态下短时血压变异不相关。结论提示血压变异性增大是高血压患者的一个重要的临床特征，长时血压变异可能与某些靶器官（心、肾）损害有关
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| 关 键 词： | 高血压；血压变异；靶器官损害；动态血压监测 |
Relationship between Blood Pressure Variability and Target Organs Damage in Hypertensive Patients |
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| Shangguan Xinhong, Zhang Weizhong. Relationship between Blood Pressure Variability and Target Organs Damage in Hypertensive Patients[J]. Chinese Journal of Hypertension, 1998, 6(3): 181-184 |
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| Authors: | Shangguan Xinhong Zhang Weizhong |
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| Abstract: | Aim To investigate the relationship between blood pressure variability(BPV) and target organs damage(TOD) in essential hypertensive patients. Methods Sixty hypertensive patients were studied with ambulatory BP monitoring and BP monitoring in states of rest and mental and physical exercise. Left ventricular mass index(LVMI) and 24 hour microalbuminuria(MAU) were examined. The standard deviation(SD) from mean blood pressure were taken as index of BPV. Results BPV was significantly correlated with BP level. Long term BPV was higher in hypertensive than in normal controls. Short term BPV in the mental stress was also higher in hypertensives.as also higher in hypertensive. Long term BPV was related to LVMI and MAU. Short term BPV neither in rest nor in stress related to LVMI and MAU. Conclusion An increased long term BPV is associated with a higher percentage of target organ damage. |
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| Keywords: | hypertension blood pressure variability taget organ damage ambulatory blood pressure monitoring |
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