急性心肌梗死近20年住院临床诊治和病死率的比较分析

目的了解本院20年间急性心肌梗死（AMI）的病死率及其影响因素的改变。方法对我院1980-1983年134例、1990-1993年354例和2000-2003年817例急性心肌梗死患者的资料进行比较分析。结果住院病死率从1980-1983年的22．4％降至1990-1993年的14．4％直至2000-2003年的9．2％（P〈0．01）。男性患者病死率降低明显（P〈0．01）。有利于病死率降低的因素有：年龄〈60岁,初发心肌梗死,心脏骤停的抢救成功率和血管再灌注治疗。不利因素为女性。结论20年间的AMI药物治疗内容及血管再灌注治疗的进展,致使AMI住院病死率的明显下降。

Comparable analysis of in-hospital mortality in patients with acute myocardial infarction

Objective To investigate the change of the mortality of AMI and influence factors within 20 years.Methods Clinic data of 134 AMI patients from 1980 to 1983, 354 AMI patients from 1990 to 1993 and 817 AMI!patients from 2000 to 2003 were comparably analyzed.Results In hospital mortality of AMI was 22.4% from 1980 to 1983, 14.4% from 1990 to 1993 and 9.2% from 2000 to 2003, respectively (P<0.01). The decrease of in-hospital mortality in male was more significant than in female (P<0.01). The corresponding factors for decrease of mortality were younger than 60 years old, first onset of AMI, successful rescue of cardiac arrest and reperfusion management of infarction relative artery. The disadvantage factor was female.Conclusions Improvement of medical and reperfusion management of AMI conduced in significant decreases of hospital mortality.