A monoclonal antibody to platelet glycoprotein IIb induces aggregation of platelet rich plasma |
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Authors: | P Perutelli P Marchese P G Mori |
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Affiliation: | Divisione di Ematologia e Oncologia, Istituto G. Gaslini, Genova, Italy. |
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Abstract: | The monoclonal antibody (MAb) GAP 5.9 directed against platelet glycoprotein IIb is described. This MAb is able to induce aggregation of platelet rich plasma in the absence of further stimuli and likely recognizes a glycoprotein epitope not closely related to calcium binding sites on the molecule. |
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