| 喹诺酮类药物的研究进展 |
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| 引用本文： | 钱志平 卢洪洲. 喹诺酮类药物的研究进展[J]. 世界感染杂志, 2005, 5(5): 432-435 |
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| 作者姓名： | 钱志平 卢洪洲 |
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| 作者单位： | 复旦大学附属上海市公共卫生中心ICU室,上海201508 |
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| 摘 要： | 喹诺酮类抗生素在临床使用已有40多年，它对人类控制微生物感染产生了巨大的作用。本文介绍了喹诺酮类抗生素的作用机制、分子结构与抗菌活性的关系、不良反应及耐药机制。
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| 关 键 词： | 喹诺酮类药物 不良反应 突变 耐药 |
| 文章编号： | 1562-3122（2005）05-0432-04 |
| 收稿时间： | 2005-09-12 |
| 修稿时间： | 2005-10-10 |
Advance in the research of Quinolone antibacterial |
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| QIAN Zhi-ping, LU Hong-zhou. Advance in the research of Quinolone antibacterial[J]. World Journal of Infection, 2005, 5(5): 432-435 |
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| Authors: | QIAN Zhi-ping LU Hong-zhou |
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| Abstract: | The quinolone antibacterial has generated considerable interests in controlling microbe infection since it was firstly applied into clinic practice more than 40 years ago. In this article, molecular mechanisms of action, molecular structure and antimicrobial activity, adverse events, mechanisms of resistance to quinolones were reviewed. |
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| Keywords: | quinolones antibacterial adverse events mutation drug resistance |
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