吸烟对男性急性心肌梗死患者直接经皮冠状动脉介入治疗心肌灌注及预后的影响

目的 观察吸烟对男性急性心肌梗死患者直接经皮冠状动脉介入治疗(PCI)心肌灌注及预后的影响.方法 选取513 例接受直接PCI治疗的急性ST段抬高心肌梗死男性患者,根据是否吸烟及吸烟指数(SI)随机分为4个组:A组为不吸烟组,B组SI＜200,C组SI 200～400,D组SI＞400.比较各组患者PCI术后即刻心肌灌...

Effect of smoking on myocardium reperfusion and clinical outcomes in patients with acute ST segment elevation myocardial infarction after primary percutaneous coronary intervention

Objective To explore the effect of smoking on myocardium perfusion and clinical outcomes in patients with acute ST segment elevation myocardial infarction （STEMI） after primary pcrcutaneous coronary intervention （PCI）. Methods A total of 513 patients with STEMI underwent primary PCI were divided into 4 groups according to the smoking index （SI）：group A, non-smoker, group B, SI〈200, group C, 200〈SI〈400 and group D, SI〉400. Myocardium reperfusion and left ventricular remodeling and dysfunction and major adverse cardiovascular events （MACE） in one year were compared between smoker and non-smoker. Results The corrected TIMI frame count （CTFC） and ST resolution were worse in smoker compared with non-smoker（P〈0.01 ）. Left ventricular remodeling and dysfunction and MACE in one year were worse in smoker compared with non-smoker（P〈0.01 ）. Conclusion Smoking on STEMI patients treated with primary PCI is associated with reduced myocardium perfusion. Abnormal myocardium perfusion might contribute to the poor clinical outcomes.