Foxpl及Ki-67在皮肤基底细胞癌的表达 |
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引用本文: | 吕明芬,黄卡特,李秉煦,徐云升. Foxpl及Ki-67在皮肤基底细胞癌的表达[J]. 中国麻风杂志, 2011, 0(5): 311-313 |
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作者姓名: | 吕明芬 黄卡特 李秉煦 徐云升 |
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作者单位: | 温州医学院附属第一医院,325000 |
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基金项目: | 国家自然科学基金(编号:30972800) |
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摘 要: | 目的:检测皮肤基底细胞癌(BCC)组织中Foxpl和Ki一67蛋白的表达。方法:采用免疫组化方法检测BCC组织石蜡切片中Foxpl和Ki-67蛋白的表达。结果:40例BCC标本中Foxpl蛋白的表达率为82.5%,Ki-67蛋白的表达率为75%,均显著高于对照组(均P〈O.01)。结论:Foxpl和Ki-67可能参与BCC的发生和发展。
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关 键 词: | Foxpl Ki-67 皮肤基底细胞癌 |
Expression of Foxpl and Ki - 67 in basal cell carcinonm |
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Affiliation: | Lv MinglCen , Huang Kate, Li Bingxu , et al . Department of Dermatology, First Aliated Hospital of Wenzhou Medi- cal College, Wenzhou , 325000 |
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Abstract: | Objective: To detect the expression of Foxpl and Ki- 67 in basal cell carcinoma (BCC). Method: The expression of Foxpl and Ki - 67 proteins was detected by immunohistochemical staining in 40 cases of BCC. Results: The positivity rates of Foxpl and Ki - 67 in BCC were 82.5% and 75% respectively, which were significandy higher than those in normal skin. Conclusion: Foxpl and Ki - 67 may be involved in the pathogenesis of BCC. |
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Keywords: | Foxpl Ki - 67 Basal cell carcinoma |
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