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Foxpl及Ki-67在皮肤基底细胞癌的表达
引用本文:吕明芬,黄卡特,李秉煦,徐云升. Foxpl及Ki-67在皮肤基底细胞癌的表达[J]. 中国麻风杂志, 2011, 0(5): 311-313
作者姓名:吕明芬  黄卡特  李秉煦  徐云升
作者单位:温州医学院附属第一医院,325000
基金项目:国家自然科学基金(编号:30972800)
摘    要:
目的:检测皮肤基底细胞癌(BCC)组织中Foxpl和Ki一67蛋白的表达。方法:采用免疫组化方法检测BCC组织石蜡切片中Foxpl和Ki-67蛋白的表达。结果:40例BCC标本中Foxpl蛋白的表达率为82.5%,Ki-67蛋白的表达率为75%,均显著高于对照组(均P〈O.01)。结论:Foxpl和Ki-67可能参与BCC的发生和发展。

关 键 词:Foxpl  Ki-67  皮肤基底细胞癌

Expression of Foxpl and Ki - 67 in basal cell carcinonm
Affiliation:Lv MinglCen , Huang Kate, Li Bingxu , et al . Department of Dermatology, First Aliated Hospital of Wenzhou Medi- cal College, Wenzhou , 325000
Abstract:
Objective: To detect the expression of Foxpl and Ki- 67 in basal cell carcinoma (BCC). Method: The expression of Foxpl and Ki - 67 proteins was detected by immunohistochemical staining in 40 cases of BCC. Results: The positivity rates of Foxpl and Ki - 67 in BCC were 82.5% and 75% respectively, which were significandy higher than those in normal skin. Conclusion: Foxpl and Ki - 67 may be involved in the pathogenesis of BCC.
Keywords:Foxpl  Ki - 67  Basal cell carcinoma
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