| 铁代谢调节及其相关疾病 |
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| 引用本文： | 张陆阳,张丹凤,潘崚. 铁代谢调节及其相关疾病[J]. 国际输血及血液学杂志, 2017, 40(1). DOI: 10.3760/cma.j.issn.1673-419X.2017.01.013 |
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| 作者姓名： | 张陆阳 张丹凤 潘崚 |
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| 作者单位： | 四川大学华西医院血液科,成都,610041 |
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| 摘 要： | 铁原子在氧化还原反应中能够转运电子,因此对许多生理过程必不可少.过去20年,遗传性铁过载、铁缺乏、铁分布异常致病基因的发现,以及对铁稳态相关调节机制的进一步研究,使我们对人类机体内铁稳态的认识更为深刻.现结合相关文献,就铁代谢、铁稳态调节机制及其相关疾病的研究进展进行综述.
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| 关 键 词： | 铁代谢障碍 铁超负荷 贫血,缺铁性 铁调素 |
Iron metabolism regulation and its related diseases |
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| Zhang Luyang,Zhang Danfeng,Pan Ling. Iron metabolism regulation and its related diseases[J]. International Journal of Blood Tranfusion and Hematology, 2017, 40(1). DOI: 10.3760/cma.j.issn.1673-419X.2017.01.013 |
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| Authors: | Zhang Luyang Zhang Danfeng Pan Ling |
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| Abstract: | Iron is a kind of essential metal for many organisms due to its ability to transfer electrons in reduction/oxidation reaction.Over the last 2 decades,the discovery of mutations in genes leading to hereditary disorders of iron overload,iron deficiency,and iron maldistribution have accelerated our understanding of human iron homeostasis.This article will review the iron metabolism,the regulatory mechanism of iron homeostasis,and its related diseases according to pertinent literatures. |
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| Keywords: | Iron metabolism disorders Iron overload Anemia,iron-deficiency Iron metabolism Iron metabolism disorders Hepcidins |
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