A highly sensitive and selective fluorescent probe for quantitative detection of Al3+ in food,water, and living cells |
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| Authors: | Qian Jiang Mingxin Li Jie Song Yiqin Yang Xu Xu Haijun Xu Shifa Wang |
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| Affiliation: | Nanjing Forestry University, China ; Department of Chemistry and Biochemistry, University of Michigan-Flint, USA ; Nanjing Forestry University, College of Chemical Engineering, China ; Institute of Chemical Engineering, Nanjing Forestry University, China |
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| Abstract: | ![]()
Three novel β-pinene-based fluorescent probes 2a–2c were designed and synthesized for the selective detection of Al3+. Probe 2a showed higher fluorescence intensity toward Al3+ than the other two compounds. Probe 2a determined the concentration of Al3+ with a rapid response time (45 s), wide pH range (pH = 1–9), excellent sensitivity (LOD = 8.1 × 10−8 M) and good selectivity. The recognition mechanism of probe 2a toward Al3+ was confirmed by 1H NMR, HRMS and DFT analysis. Probe 2a was successfully used as a signal tool to quantitatively detect Al3+ in food samples and environmental water samples. Furthermore, probe 2a was successfully utilized to label intracellular Al3+, indicating its promising applications in living cells.Probe 2a exhibiting high sensitivity, good selectivity, wide pH range, lower detection limit, and rapid detection for Al3+, probe 2a was applied for the successful detection of Al3+ in water samples, food samples and HeLa cells. |
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