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| 赛葵的解热镇痛抗炎作用 | |
| 引用本文： | 罗谋伦,钟文,黄世英,谢崇源. 赛葵的解热镇痛抗炎作用[J]. 中草药, 1999, 30(6): 436-438 |
| 作者姓名： | 罗谋伦 钟文 黄世英 谢崇源 |
| 作者单位： | 1. 北京医科大学药理学系,100083 2. 广西半宙制药集团 3. 广西中医学院药学系 |
| 摘 要： | 采用伤赛－融伤赛菌苗致热家兔法研究赛葵的解热作用，热板法和扭体法研究赛葵的镇痛作用，二甲苯致炎鼠耳肿胀法和腹腔毛细血管通透性法研究赛葵的抗炎作用。结果表明：赛葵全草１０、２０ｍｇ／ｋｇ ｉｇ给药能降低发热家兔的体温，延长小鼠的痛反应时间，减少扭体鼠数和扭体次数，２０ｍｇ／ｋｇ抑制鼠耳的肿胀及抑制小鼠腹腔毛细血管通透性；赛葵根１０ｍｇ／ｋｇ ｉｇ给药能降低发热家兔的体温，抑制鼠耳的肿胀，降低小鼠腹腔 |
| 关 键 词： | 赛葵 解热 镇痛 抗炎 药理 |
| 收稿时间： | 1998-08-20 |
Antipyretic, Analgesic and Anti-inflammatory Effects of Coromadel CoastFalsemallow (Malvastrum coromandelianum) |
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| Lou Moulun,Zhong Wen,Huang Shiying. Antipyretic, Analgesic and Anti-inflammatory Effects of Coromadel CoastFalsemallow (Malvastrum coromandelianum)[J]. Chinese Traditional and Herbal Drugs, 1999, 30(6): 436-438 | |
| Authors: | Lou Moulun Zhong Wen Huang Shiying |
| Affiliation: | Department of Pharmacology, Beijing University of Medical Sciences, Beijing 100083;Department of Pharmacology, Beijing University of Medical Sciences, Beijing 100083 |
| Abstract: | Antipyretic, analgesic and anti-inflammatory effects of Malvastrum coromandelianum (L.) Garcke were tested by fever caused by typhoid-paratyphoid vaccine in rabbits ; hot-plate, writhing, ear edema, and abdominal capillary permeability of mice. Results of the study showed that both aqueous extract of whole plant or root of M. coromandelianum (L.) Gurcke at doses of 10, 20 mg/kg, po equivalent to the crude plant could lower rabbit fever (P<0. 05, P |
| Keywords: | Malvastrum coromandelianum (L. ) Garcke antipyretic analgesic and anti--inflammatory actions |
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