冠心病患者合并糖尿病危险因素及病变特点

目的:比较合并糖尿病(DM)的男女冠心病(CHD)患者危险因素及病变特点,以提高诊治水平。方法:选择冠状动脉造影确诊合并DM的CHD患者88例。男48例,女40例,回顾性分析两组危险因素及冠状动脉病变特点,支架植入资料。结果:1男性组吸烟(79.2%)及具有三个以上危险因素者(83.3%)明显高于女性组;高血压、家族史、高脂血症无显著性差异。2男性组前降支病变显著高于女性组(77.1%VS40.0%,P<0.01);女性组右冠状动脉病变显著高于男性组(80.0%VS50.0%,P<0.05);3女性组直径2.5～2.75mm血管的病变长度(mm)显著长于男性组(32.0±2.4VS19.4±8.7,P<0.01),女性组在前降支及右冠状动脉植入的支架的长度(mm)显著长于男性组(28.0±5.8VS21.2±4.3,23.7±9.5VS17.2±5.6,P<0.01)。结论:吸烟是伴有DM的男性CHD患者重要危险因素,DM在老年女性CHD患者中发挥重要作用。女性CHD患者主要累及较小的冠状动脉且病变弥漫。

The risk fuctovs and lesion chavacteristiss patients with coronary heart disease and diabetes

Objective： To compare the risk factors and the coronary artery lesions between the male and female patients with coronary heart disease （CHD） and diabetes mellitus （DM） Method： 48 male and 40 female patients with DM were identified as CHD by coronary angiography. The risk factors, coronary artery lesions and the results of stents were analyzed. Result： ①Smoking （79.20%） and having more than three risk factors in male patients were higher than those in females, but the DM, hyperlipdemia andhypertension were balanced between the two groups. ② The lesions in left descending artery（LAD） in male patients were higher than those in females（77.1% VS 40.0% ,P〈0.01）, but the lesions in right coronary artery （RCA） were lower （80.0% VS 50. 0%,P 〈0. 05）. ③ The lesions in 2. 5-2. 75mm artery in female patients were longer than those in males（32. 0±2.4 VS 19.4±8. 7,P 〈0.01） and the stents planting in the LDA and RCA in female patients were longer （28.0±5.8 VS 21.2±4.3,23.7±9.5 VS 17.2±5.6,P 〈0.01）. Conclusion： Smoking is an important risk factor in male patients ; DM plays an important role in the old female patients and the lesions in them are severe and diffuse.