单鼻孔蝶窦入路显微手术治疗垂体腺瘤

目的探讨经蝶窦入路治疗垂体腺瘤临床意义。方法2000年9月至2006年9月共选择收治垂体腺瘤患者56例,术前均进行冠状CT、MR I检查,并行内分泌学检查,均行单鼻孔蝶窦入路显微手术治疗。术后随访6～36个月。结果肿瘤全切47例,次全切7例,部分切除2例。术后症状及内分泌检查改善54例,17例出现一过性尿崩5例出现并发症,包括鼻中隔穿孔,鼻黏膜感染,脑脊液漏。2例一年后复发。结论经蝶窦手术治疗垂体腺瘤创伤小,操作简单,安全,肿瘤切除完全,住院时间短,费用低。

Resection of pituitary adenoma via endonasal trans - sphenoidal sinus approach

Objective To explore the clinical significance of resection of pituitary adnomas via endonasal trans-sphenoidal sinus approach.Methods 56 patients with pituitary adenoma were treated by resection via endonasal trans-sphenoidal sinus approach from September 2000 to September 2006. All the patients received coronal CT and MRI scan,and endocrinological examinations before operation and followed up for 6-36 months after operation.Results The tumor was removed totally in 47 patients,subtotally in 7 patients,and partially in 2 patients.54 patients achieved an improvement in clinical and endocrinological examination.Postoperative complications were found in 5 patients,including nasal septum perfortion,nasal mucosal infection and cerebrospinal rhinorrhea.2 patients relapsed 1 year after operation.Conclusion The resection of pituitary adnomas via endonasal trans-sphenoidal sinus approach is minimal invasive,simple and safe,with low cost and relatively high total resection rate,and shorter hospital stay.