| 增殖细胞核抗原在涎腺粘液表皮样癌中的表达及其临床意义 |
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| 引用本文： | 王青. 增殖细胞核抗原在涎腺粘液表皮样癌中的表达及其临床意义[J]. 泰山医学院学报, 2010, 31(5): 361-363 |
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| 作者姓名： | 王青 |
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| 作者单位： | 泰山医学院附属泰山医院病理科,山东,泰安,271000 |
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| 摘 要： | 目的探讨增殖细胞核抗原（PCNA）在涎腺粘液表皮样癌中的表达及临床意义。方法选择30例涎腺粘液表皮样癌石蜡标本,用免疫组化方法（SABC）测定PCNA表达.结果PCNA在涎腺粘液表皮样癌中的表达阳性率为（75.47士17.83）%。PCNA标记指数与涎腺粘液表皮样癌的分化程度、淋巴结转移均显著相关。结论 PCNA可能成为判断涎腺粘液表皮样癌恶性程度及预后的有效指标。
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| 关 键 词： | 增殖细胞核抗原 涎腺粘液表皮样癌 免疫组化 |
Clinical significance of expression of proliferating cell nuclear antigen in salivary glands mucoepidermoid carcinoma |
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| WANG Qing. Clinical significance of expression of proliferating cell nuclear antigen in salivary glands mucoepidermoid carcinoma[J]. Journal of Taishan Medical College, 2010, 31(5): 361-363 |
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| Authors: | WANG Qing |
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| Affiliation: | WANG Qing (Dept.of Pathology,Taian City Central Hospital,Taian 271000,China) |
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| Abstract: | Objective：To study the clinical value of proliferating cell nuclear antigen（PCNA） expressed in salivary glands mucoepidermoid carcinoma.Methods： 30 cases of salivary glands mucoepidermoid carcinoma tissue were examined by immunohistochemical method.Results： The positive rates of PCNA expression in salivary glands adenocarcinoma tissue was 75.47士17.83%.The expression of PCNA was closely correlated with the tumor-differentiation and lymph node metastasis.Conclusion： It is suggested that PCNA may serve as a marker for evaluating the malignancy and prognosis of salivary glands mucoepidermoid carcinoma. |
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| Keywords: | proliferating cell nuclear antigen salivary glands mucoepidermoid carcinoma immunohistochemistry |
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