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DIFFERING EFFECTS OF CARBOHYDRATE, FAT AND PROTEIN ON THE RATE OF ETHANOL METABOLISM
Authors:ROGERS, JO   SMITH, JILL   STARMER, G.A.   WHITFIELD, J.B.
Affiliation:*Departments of Dietetirs University of Sydney NSW 2006, Australia
"{dagger}"Departments of Clinical Biochemistry, Royal Prince Alfred Hospital Camperdown, NSW 2050, Australia
"{ddagger}"Department of Pharmacology, University of Sydney NSW 2006, Australia
Abstract:The rate of metabolism of ethanol in humans has been assessedby intravenous infusion of ethanol/saline under feedback controlto maintain a constant blood alcohol concentration. After equilibration,meals consisting predominantly of carbohydrate, fat or proteinwere eaten and changes in ethanol metabolic rate were found.Carbohydrate caused a significant increase in this rate andfat or protein caused small but non-significant decreases. Infusionof ethanol/saline resulted in a temporary fall in plasma freefatty acid levels and a steady rise in plasma triglycerides.The changes in alcohol metabolism following carbohydrate cannotbe accounted for by changes in insulin, free fatty acid or lactate/pyruvatelevels.
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