冠状动脉旁路移植术后中期患者生命质量研究

目的 运用3个国外的生命质量(QOL)问卷对我院接受冠状动脉旁路移植术的患者进行QOL的研究,检验所使用问卷的信度和效度,并分析影响QOL的因素.方法 选择2001年1月至2002年1月于我院接受冠状动脉旁路移植术的患者,以书信的形式对287例患者发送QOL问卷,对问卷进行信度和效度的分析,并对影响QOL的因素进行分析.结果 共有273例患者寄回了问卷,3个QOL问卷的信度分析结果内部一致性系数分别为0.81、0.75、0.78.3个QOL问卷的结构效度分析结果显示存在不同程度的统计学相关性.对影响QOL的相关因素分析,3个问卷均提示术前加拿大心血管学会(CCS)心绞痛分级较严重患者的QOL低于术前CCS心绞痛分级较轻微患者的QOL.其中西雅图心绞痛问卷的"活动能力"、"疾病主观感受"亚组以及诺丁汉健康问卷的"社会孤独感"、"活动能力"亚组差异明显.结论 术前CCS心绞痛分级是影响冠状动脉旁路移植术后患者QOL的因素.

Quality of life five years after coronary artery bypass grafting

Objective The quality of life(QOL)5 years after coronary artery bypass grafting (CABG)was evaluated by NHP,SAQ and DASI questionnaires.Methods NHP,SAQ and DASI questionnaires were mailed to 287 patients who received CABG in our department between Jan 2001 and Jan 2002.The reliability and construct validity of the questionnaires and the influence factor of QOL were analyzed.Results Two hundred and seventy-three patients(95％)responded to the questionnaires.The reliability of three questionnaires about QOL was 0.81,0.75 and 0.78,respectively.QOL at 5 years post CABG was significantly better in CCS Ⅰ/Ⅱpatients than CCSⅢ/Ⅳ patients'according to SAQ.Exertional scale and disease perception scale according to SAQ,social isolation and physical abilities to NHP also significantly related to QOL 5 years post CABG.Conclusions All 3 questionnaires had high reliability and statistical validity for evaluating QOL.CCS angina degree affect the quality of life in patients 5 years post CABG.