家兔小脑中央核向脊髓直接投射的研究

本实验将WGA-HRP分別注入家兔脊髓一侧的颈、胸、腰等不同节段,逆行追踪小脑中央各核向脊髓的直接投射。结果表明,小脑中央核的标记神经元恒定地见于颈段(C_1～C_4)注入例动物,而未见于下颈段(C_6～C_8)和胸腰段注入例动物。标记神经元仅出现于注入侧对侧的小脑顶核及间位核的尾侧部。研究结果提示,家兔小脑顶核及间位核的尾侧部,有向颈髓的直接越边投射。本结果为进一步探讨小脑对躯体运动的调节功能提供形态学基础。

DIRECT SPINAL PROJECTIONS FROM THE CEREBELLAR NUCLEI IN THE RABBIT

The direct spinal projections from the cerebellar nuclei in the rabbit were retro gradely traced by unilateral injection of WGA-HRP into different levels of the spinal cord, including the cervical, thoracic and lumbar segments. The labeled neurons in the cerebellar nuclei were constantly seen in those animals, in which the upper cervical segments (C_(2-4)) were injected. No labeled neurons could be found in the cerebellar nuclei following injection into the lower cervical cord (C_(6-8)) or more caudal segments. All labeled neurons were located in the caudal parts of the fastigial and the interposed nuclei on the side contralateral to the injection. The results show that there are crossed projections from the cerebellar nuclei directly to the upper cervical cord. This study provide certain morphological evidences for further investigation of some aspects of cerebellar functions on motor coordination.