Hodgkin's disease of the thoracic vertebrae |
| |
| Authors: | Masashi Uehara Jun Takahashi Hiroki Hirabayashi Jun Kitahara Tetsuyoshi Kamijyo Sohei Ebara Hiroyuki Kato |
| |
| Affiliation: | 1. Department of Orthopaedic Surgery, Shinshu University, School of Medicine, 3-1-1 Asahi, Matsumoto City, Nagano 390-8621, Japan;2. Department of Orthopaedic Surgery, Shonam Fujisawa Tokushukai Hospital, 1-5-1 Tsujikandai, Fujisawa City, Kanagawa 251-0041, Japan;1. The Musculoskeletal Research Center, Department of Orthopedic Surgery, The Children''s Hospital, 13123 E. 16th Ave., B060, Aurora, CO 80045, USA;2. Department of Orthopedic Surgery, University of Colorado, 13123 E. 16th Ave., B060, Aurora, CO 80045, USA;3. Pediatric Research Institute, The Children''s Hospital, 13123 E. 16th Ave., B060, Aurora, CO 80045, USA;1. Department of Orthopaedic Surgery, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennoudai, Tsukuba, Ibaraki 305-8575, Japan;2. Department of Spine and Orthopaedic Surgery, Japanese Red Cross Medical Center, 4-1-22 Hiroo, Shibuya-ku, Tokyo 150-8935, Japan;1. Division of Applied Bioscience and Biotechnology, Institute of Environmentally Friendly Agriculture (IEFA), Chonnam National University, Gwangju 500-757, Republic of Korea;2. Division of Plant Biotechnology, Institute of Environmentally Friendly Agriculture (IEFA), Chonnam National University, Gwangju 500-757, Republic of Korea |
| |
| Abstract: | Background contextHodgkin's disease rarely occurs in the spine, which is usually a setting for the advanced form of the disease.PurposeTo describe an unusual case of isolated, primary spinal Hodgkin's disease and to draw attention to this disease as a possible diagnosis in patients with mixed inflammatory cell infiltrate lesions located in the thoracic spine.Study design/settingA case report of a 28-year-old woman who presented with back pain and progressive weakness in the lower extremities as a result of spinal cord compression from Hodgkin's disease of the thoracic vertebrae.MethodsWe report a new case of spinal cord compression resulting from Hodgkin's disease of the thoracic vertebrae. Decompression surgery was performed in the patient, followed by antibiotic treatment.ResultsAntibiotic therapy temporarily improved inflammation and fever. However, magnetic resonance imaging (MRI) evaluation showed that the inflammatory reaction in the lesion was not completely resolved. The disease progressed and later investigations revealed Hodgkin's disease, which improved with a course of chemotherapy and radiation.ConclusionsHodgkin's disease should be considered in the differential diagnosis of spinal neoplastic lesions with clinical features similar to spondylitis. Because MRI evaluation showed that the vertebral disc was maintained in this case, the presence of a tumor rather than inflammation should have been suspected. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
