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颜面播散性粟粒性狼疮皮损中TGFβ_1的检测
引用本文:胡亚红,郑凤兰,高顺强,王琪,王婷琳. 颜面播散性粟粒性狼疮皮损中TGFβ_1的检测[J]. 中国皮肤性病学杂志, 2005, 19(1): 17-18
作者姓名:胡亚红  郑凤兰  高顺强  王琪  王婷琳
作者单位:1. 北京民航总医院皮肤科,北京,100025
2. 河北医科大学第四医院皮肤科,河北,石家庄,050011
摘    要:
目的 探讨转化生长因子β1 (TGFβ1 )在颜面播散性粟粒性狼疮 (LMDF)发病中的作用。方法 采用免疫组化SP法检测 20例LMDF皮损中TGFβ1,并以 10例正常皮肤组织作对照。结果 LMDF组TGFβ1 阳性率和着色程度均明显高于对照组(P<0. 05)。结论 TGFβ在LMDF的发病中可能起重要作用。

关 键 词:颜面播散性粟粒性狼疮  TGFβ1  免疫组化
文章编号:1001-7089(2005)01-0017-02

Detectian of TGFβ1 in the Lesion of Lupus Miliaris Disseminatus Faciei
HU Ya-hong,ZHENG Feng-lan,GAO Shun-qiang,et al. Detectian of TGFβ1 in the Lesion of Lupus Miliaris Disseminatus Faciei[J]. The Chinese Journal of Dermatovenereology, 2005, 19(1): 17-18
Authors:HU Ya-hong  ZHENG Feng-lan  GAO Shun-qiang  et al
Abstract:
Objective To discuss the function of TGFβ 1 in the course of LMDF.Methods To detect and measure TGFβ 1 in 20 lesion samples of LMDF by using the method of SP immunohistochemistry,and compare them with 10 normal samples.Results TGFβ 1 in the LMDF group were higher than that of the comparative group(P<0.05).Conclusion TGFβ 1 plays an important role during the beginning and development of LMDF.
Keywords:LMDF  TGFβ 1  Immunohistochemistry
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