| 乙肝病毒前S1抗原的临床应用评价 |
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| 引用本文： | 方有兵,沈际佳,陆应玉,金先彬. 乙肝病毒前S1抗原的临床应用评价[J]. 安徽医学, 2006, 27(3): 201-202 |
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| 作者姓名： | 方有兵 沈际佳 陆应玉 金先彬 |
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| 作者单位： | 1. 230022,合肥,安徽医科大学第一附属医院检验科
2. 安徽医科大学基础医学院 |
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| 摘 要： | 目的探索乙肝病毒前S1抗原与肝脏损伤程度的关系,及与乙肝病毒DNA复制活跃程度的关系。方法乙肝病毒前S1抗原用ELISA方法检测,丙氨酸氨基转移酶用紫外-乳酸脱氢酸法检测,HBV-DNA测定运用荧光实时定量检测方法。结果乙肝病毒前S1抗原阳性与ALT升高有正相关,乙肝病毒前S1抗原阳性与HBV-DNA阳性有显著性相关。结论乙肝病毒前S1抗原可以用来评价肝脏功能指标,也可作为机体内乙肝病毒复制活跃程度指标。
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| 关 键 词： | 乙肝病毒前S1抗原 肝损伤 病毒复制 |
| 收稿时间： | 2005-08-12 |
| 修稿时间： | 2005-08-122006-10-01 |
Clinical Evaluation with Pre-S1 antigen of hepatitis B virus |
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| Fang Youbing ,Shen Jijia ,Lu Yingyu ,et al. Clinical Evaluation with Pre-S1 antigen of hepatitis B virus[J]. Anhui Medical Journal, 2006, 27(3): 201-202 |
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| Authors: | Fang Youbing Shen Jijia Lu Yingyu et al |
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| Affiliation: | Department of Laboratory Medicine ,the First Affiliated Hospital of Anhui Medical University, Hefei 230022 |
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| Abstract: | Objective Explore Pre-S1 antigen of hepatitis Bvirus the relation with liver damage level, and with hepatitis B virus DNA reconstructed active level.Methods Pre-S1 antigen of hepatitis Bvirus with ELISA method, it is ultraviolet that ALT use LD method, HBV-DNA was determined by fluorescence quantitative PCR(FQ-PCR) assay.Results Pre-S1 antigen of hepatitis B virus and ALT go up have the positive that closes,Pre-S1 antigen of hepatitis B virus positive and HBV-DNA positive do have significant relationship. Conclusion Pre-S1 antigen of hepatitis B virus can be used to appraise liver function, fit for in organism hepatitis B virus reconstructed active level index. |
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| Keywords: | Pre- S1 antigen Liver damage HBV replication |
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