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在分化性甲状腺癌中检测血清甲状腺球蛋白的临床价值
引用本文:吴社华 王弘士. 在分化性甲状腺癌中检测血清甲状腺球蛋白的临床价值[J]. 上海医学, 1995, 18(3): 125-127
作者姓名:吴社华 王弘士
作者单位:上海铁道医学院附属甘泉医院普外科,上海医科大学附属肿瘤医院外科
摘    要:
本文54例分化性甲状腺癌中,治疗前血清甲状腺球蛋白(STg)大于15ng/ml者16例,其STg升高与肿瘤大小(P〈0.001)和血运转移(P〈0.001)有关。16例STg升高者中,11例行患侧腺叶切除,术后9例STg降至正常范围,另2例STg仍较高者伴有残留转移病灶。因此我们认为分化性甲状腺癌中升高的STg多为肿瘤组织异常释放所致,腺叶切除术后较高水平的STg常提示有残余或转移病灶,对治疗监测

关 键 词:血清 甲状腺球蛋白 甲状腺肿瘤 诊断

CLINICAL VALE OF SERUM THYROGLOBULIN MEASUREMENT IN DIFFERENTIATED THYROID CARCINOMA
Wu She hua Wang Hong shi Gan Quan Hospital,Shanghai Railway Medical College Cancer Hospital,shanghai Medical University. CLINICAL VALE OF SERUM THYROGLOBULIN MEASUREMENT IN DIFFERENTIATED THYROID CARCINOMA[J]. Shanghai Medical Journal, 1995, 18(3): 125-127
Authors:Wu She hua Wang Hong shi Gan Quan Hospital  Shanghai Railway Medical College Cancer Hospital  shanghai Medical University
Abstract:
he serum thyroglobulin(Tg)in 54 patients with differentiated thyroid carcino Ma were determined.Elevated serum Tg occurred in 16 of 54 patients before treatment, and the elevation was related to tumor size and distant metastases(P<0.001). In 9of 11 patients with serum Tg elevation the serum Tg levels fell to normal afterhemithyroidectomy, except for 2 with metastatic tumor. The results showed thatthe elevation of serum Tg in differentiated thyroid carcinoma might be an abnormalsecretron by tumor tissues, and elevated serum Tg following lobectomy might be anindicator of the presence of residual or metastatic tumor.
Keywords:serum thyroglobulin thyroid carcinoma  
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