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灵芝孢子油的稳定性考察
引用本文:曾荣华,李菁,刘翠红,宋晓燕. 灵芝孢子油的稳定性考察[J]. 中国实验方剂学杂志, 2014, 20(18): 23-25
作者姓名:曾荣华  李菁  刘翠红  宋晓燕
作者单位:广州白云山汉方现代药业有限公司中药提取分离过程现代化国家工程研究中心,广州,510240
基金项目:国家“重大新药创制”科技重大专项(2011ZX09401-404);广州市科技计划项目(201300000084)
摘    要:
目的:考察灵芝孢子油加速试验后的质量变化。方法:以酸值、过氧化值、总三萜及甘油三油酸酯含量为评价指标,考察灵芝孢子油加速0,1,2,3,6个月后的质量变化。采用HPLC测定甘油三油酸酯含量,Kromasil-C18色谱柱(4.6 mm×200 mm,5μm),流动相乙腈-异丙醇(53∶47),流速0.5 mL·min-1,蒸发光散射检测器检测,柱温30℃。结果:与0月相比,灵芝孢子油加速6个月后,酸值呈上升趋势,上升幅度32.11%~39.27%;过氧化值呈下降趋势,下降幅度41.17%~46.67%;总三萜含量呈下降趋势,下降幅度6.72%~8.13%;甘油三油酸酯含量呈下降趋势,下降幅度3.78%~4.54%;酸值与过氧化值均符合食用植物油的卫生标准。结论:灵芝孢子油加速6个月质量较稳定。

关 键 词:灵芝孢子油  稳定性  加速试验  甘油三油酸酯  总三萜
收稿时间:2014-03-28

Stability of Ganoderma Spores Oil
ZENG Rong-hu,LI Jing,LIU Cui-hong and SONG Xiao-yan. Stability of Ganoderma Spores Oil[J]. China Journal of Experimental Traditional Medical Formulae, 2014, 20(18): 23-25
Authors:ZENG Rong-hu  LI Jing  LIU Cui-hong  SONG Xiao-yan
Affiliation:National Engineering Research Center for Modernization of Extraction and Separation Process of Traditional Chinese Medicine, Guangzhou Hanfang Pharmaceutical Co. Ltd, Guangzhou 510240, China;National Engineering Research Center for Modernization of Extraction and Separation Process of Traditional Chinese Medicine, Guangzhou Hanfang Pharmaceutical Co. Ltd, Guangzhou 510240, China;National Engineering Research Center for Modernization of Extraction and Separation Process of Traditional Chinese Medicine, Guangzhou Hanfang Pharmaceutical Co. Ltd, Guangzhou 510240, China;National Engineering Research Center for Modernization of Extraction and Separation Process of Traditional Chinese Medicine, Guangzhou Hanfang Pharmaceutical Co. Ltd, Guangzhou 510240, China
Abstract:
Keywords:Ganoderma spores oil  stability  accelerated test  glycerol trioleate  total triterpenoids
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