胃癌术后胆囊结石形成原因的多因素分析

目的探讨胃癌术后胆囊结石发生的原因。方法1995至2006年间胃癌手术病例198例中36例（18．2％）发现胆囊结石，分析与胆囊结石发生有关的因素。结果全胃切除术、食物不通过十二指肠的重建术、联合脏器切除、围手术期输血的病人胆石发生率显著增高。多因素分析，无与胆囊结石发生有意义的相关因素，但相关性最大者为全胃切除、食物不通过十二指肠的重建术。结论全胃切除术、食物不通过十二指肠的重建、联合脏器切除及围手术期输血是术后胆石形成的可能因素。

Analysis of Cholelithiasis Following Radical Gastrectomy

Objective: To analyze the cause of cholelithiasis after radical gastrectomy.Methods: Cholelithiasis occured in 36(18.2%) of 198 patients who underwent radical gastrectomy during from 1995 to 2006.The factors related to cholelithiasis was analyzed by multiple regression method.Results: Cholelithiasis rate was significantly high in patients with total gastectomy,reconstuction without food going through duodenum,combined organ resection and peri-operation blood transfusion.In addition,there were no significant factors correlated with cholelithiasis by multiple regression analysis.But the most correlative factors was the operation pattern(total gastrectomy,reconstruction without food going through duodenum).Conclusion: Cholelithiasis is most likely to occur in the patients with total gastrectomy,reconstruction without food going through duodenum,combined organ resection and peri-operation blood transfusion.