| 5种中药煎剂与颗粒剂对临床分离菌株的体外抑菌作用比较 |
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| 引用本文： | 王育红,张志清,李仲兴,王秀华. 5种中药煎剂与颗粒剂对临床分离菌株的体外抑菌作用比较[J]. 中国药房, 2005, 16(17): 1354-1356 |
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| 作者姓名： | 王育红 张志清 李仲兴 王秀华 |
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| 作者单位： | 河北医科大学第二医院药品科,石家庄市,050000 |
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| 摘 要： | 目的:探讨中药煎剂与颗粒剂的生物等效性,为临床合理用药提供依据。方法:采用M-H琼脂稀释法,测定黄连、黄芩、五倍子、五味子和黄柏煎剂与颗粒剂对224株临床分离菌株的MIC50、MIC90、MIC、MBC,以比较其抑菌作用。结果:5种中药煎剂与颗粒剂都显示出不同程度的抑菌作用,以五倍子煎剂抑菌作用最强。结论:5种中药煎剂抑菌作用比相应颗粒剂抑菌作用强。
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| 关 键 词： | 中药 煎剂 颗粒剂 抑菌作用 |
| 文章编号： | 1001-0408（2005）17-1354-03 |
| 收稿时间： | 2004-12-20 |
| 修稿时间： | 2005-03-01 |
Comparison of in Vitro Bacteriostatic Action of 5 Traditional Chinese Medicine Apozems & Granules against Clinical Isolated Bacterial Strains |
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| WANG Yuhong,ZHANG Zhiqing,LI Zhongxing,WANG Xiuhua. Comparison of in Vitro Bacteriostatic Action of 5 Traditional Chinese Medicine Apozems & Granules against Clinical Isolated Bacterial Strains[J]. China Pharmacy, 2005, 16(17): 1354-1356 |
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| Authors: | WANG Yuhong ZHANG Zhiqing LI Zhongxing WANG Xiuhua |
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| Abstract: | OBJECTIVE:To discuss the bioequiavailability of traditional Chinese medicine apozems and granules and to provide references for the rational drug use in the clinic.METHODS:Coptidis rhizome,scutellaria,Chinese gall,fructus schiza_ ndrae,cortex phellodendri decotion and granules against The MIC 50 ,MIC 90 ,MIC and MBC of224strains of clinical isolated str_ ains were determined by M-H agar dilution method and the bacteriostatic actions of which were compared.RESULTS:5traditional Chinese medicine apozems and granules showed different degree of antibacterial actions,with the Chinese gall being the most potent.CONCLUSION:The apozems showed stronger antibacterial actions than the granules among the5traditional Chinese medicines. |
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| Keywords: | Traditional Chinese medicine Apozem Granules Bacteriostatic action |
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