不同品牌全自动血凝仪检测结果对比分析

目的：通过对同一临床实验室不同品牌的全自动血凝分析仪进行方法对比,探讨不同血凝分析仪之间检测结果是否具有可比性,或检测结果的偏差是否在允许的范围内。方法：收集112例新鲜血浆标本,采用ACL ADVANCE和Sysmex CA7000两种凝血分析仪,分别测定凝血酶原时间（PT）、活化部分凝血酶原时间（APTT）、凝血酶时间（TT）和纤维蛋白原（FIB）,并比对结果,以医学决定水平的系统误差来判断检测系统结果是否为临床接受,同时计算两台血凝仪各项检测结果的相关系数和直线回归方程。结果：对两种凝血分析仪检测的PT、APTT、TT及FIB结果比较,其差异均无统计学意义（t=0.974,t=0.649,t=0.765,t=1.163;P〉0.05）,且两者具有良好的相关性;医学决定水平的系统误差均小于总允许误差的1/2。结论：以ACL ADVANCE作为标准检测系统,Sysmex CA7000测定的结果具有临床可接受性,两台血凝仪检测的结果具有良好的相关性。定期对同一实验室不同凝血分析仪进行比对实验,以保证同一实验室内检验结果的可比性。

Different brand automatic instrument of coagulation test results contrast analysis

Objective： Based on the same clinical laboratory automatic blood coagulation analyzer method comparison of different brands. Discuss different between blood coagulation analyzer test results are comparable or check whether the deviation of the results in the permitted range. Method：collecting 112 cases of fresh plasma specimens, using ACL ADVANCE and Sysmex CA7000 two kinds of blood coagulation analyzer, respectively prothrombin time （PT）, activated partial prothrombin time （APTT）, thrombin time （TT） and fibrinogen （FIB）, and compare the results, to medical decision level of judging system error detection system for clinical result, and calculate the two blood coagulation instrument testing results of the correlation coefficient and linear regression equation. Results：the ACL ADVANCE and Sysmex CA7000 blood coagulation analyzer test of PT, APTT, TT and FIB result comparison, there were no statistically significant difference （t=0.974, t=0.649, t=0.765, t=1.163;P〉0.05）, the correlation coefficient respectively;Medical decision level of system error were less than half the total margin of error. Conclusion：to the ACL ADVANCE as standard test system, Sysmex CA7000 determination results have clinical acceptability, two blood coagulation test results with good correlation. Should be conducted on a regular basis in the same laboratory coagulation analyzer compares different experiments, to ensure the comparability of the same in the laboratory test results.