非淋球菌性尿道炎患者支原体和衣原体感染及耐药性分析

目的探讨海南地区皮肤科门诊泌尿生殖道衣原体（CT）和支原体感染及支原体药敏情况。方法2008-2010年本院皮肤科门诊共1627例就诊患者采用PCR法检测标本中衣原体，采用试剂盒进行支原体培养和药敏试验。结果单纯CT阳性89例，占5．47％，单纯Uu阳性1073例，占65．95％，单纯Mh阳性38例，占2．34％，MH＋Uu3例，占0．18％，CT＋Uu25例，占1．54％，CT＋MH2例，占0．12％，CT＋Uu＋MH0例。耐药情况为：Uu对四环素、美满霉素、阿奇霉素，克拉霉素及交沙霉素敏感性较好。Mh对四环素、交沙霉素及美满霉素敏感性好。结论本地区农原体及支原体感染率较高，支原体经验性治疗首选美满霉素、四环素及交沙霉素。临床医师应根据药敏实验结果选择敏感抗生素。

Analaysis on Mycoplasma and Chlamydia infection as well as the antimicrobial susceptibility of mycoplasma in patient with non-gonococcal urethritis

Objective To study the Chlamydia and Mycoplasma infection and the antimicrobial susceptibility of mycoplasma in the Department of Dermatology in Hainan province. Methods A total of 1 627 patients in the Department of Dermatology in our hospital from 2008 to 2010 were detected for Chlamydia, Mycoplasma and antimicrobial susceptibility using PCR. Results Detection revealed CT-positive alone in 89 cases (5.47%), Uu-positive alone in 1 073 cases (65.95%), Mh-positive alone in 38 cases (2.34%), MH+Uu positive in 3 cases (0.18%), CT+Uu positive in 25 cases (1.54%), CT+MH positive in 2 cases (0.12%), and CT+Uu+MH positive in 0 cases. Uu is sensitive to Tetracycline, Minocycline, Azithromycin, Clarithromycin and Josamycin, while Mh is sentitive to Tetracycline, Josamycin, and Minocycline. Conclusion The infection rate of Chlamydia and Mycoplasma in Hainan province is quite high. The selection of antibiotics should be based on the drug susceptibility test. For treating Mycoplasma infection, Minocycline, Josamycin and Tetracycline are preferred.